IQSEC1 and MAGEA3

Data Source:
BioGRID (two hybrid)

		IQSEC1	MAGEA3
Description		IQ motif and Sec7 domain ArfGEF 1	MAGE family member A3
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GO Annotations	Cellular Component	Nucleolus Synaptic Vesicle Postsynaptic Density Membrane Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding	Protein Binding Caspase Binding
	Biological Process	Actin Cytoskeleton Organization Regulation Of ARF Protein Signal Transduction Positive Regulation Of GTPase Activity Positive Regulation Of Keratinocyte Migration Dendritic Spine Development Positive Regulation Of Focal Adhesion Disassembly	Negative Regulation Of Protein Processing Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Periodontitis (DPAL) ( 24024966) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		2 interacting genes: APOE MAGEA3	16 interacting genes: ACOT7 BCL7B C17orf49 CINP DNM1L ENOX2 EXOC5 HLA-DRB1 HTT IQSEC1 KIF27 LSM2 PCYT1A RUSC1 S100A9 STAMBPL1
Entrez ID		9922	4102
HPRD ID		11052	02166
Ensembl ID		ENSG00000144711	ENSG00000221867
Uniprot IDs		A0A0C4DGT3 B4DGC5 Q6DN90	P43357
PDB IDs		3QWM 4C0A 5NLV 5NLY 6FNE	1QEW 4V0P 5BRZ
Enriched GO Terms of Interacting Partners?
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