MAGEA3 and S100A9

Data Source:
BioGRID (two hybrid)

		MAGEA3	S100A9
Description		MAGE family member A3	S100 calcium binding protein A9
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum	Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell Junction Secretory Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Protein Binding Caspase Binding	Calcium Ion Binding Protein Binding Microtubule Binding Zinc Ion Binding Antioxidant Activity Toll-like Receptor 4 Binding Calcium-dependent Protein Binding Arachidonic Acid Binding RAGE Receptor Binding
	Biological Process	Negative Regulation Of Protein Processing Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Cytokine Production Toll-like Receptor Signaling Pathway Leukocyte Migration Involved In Inflammatory Response Chronic Inflammatory Response Autophagy Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Inflammatory Response Cell-cell Signaling Positive Regulation Of Neuron Projection Development Astrocyte Development Peptidyl-cysteine S-nitrosylation Antimicrobial Humoral Response Positive Regulation Of Cell Growth Neutrophil Chemotaxis Sequestering Of Zinc Ion Response To Lipopolysaccharide Chemokine Production Autocrine Signaling Peptidyl-cysteine S-trans-nitrosylation Modulation Of Process Of Other Organism Defense Response To Bacterium Neutrophil Degranulation Innate Immune Response Regulation Of Integrin Biosynthetic Process Positive Regulation Of Inflammatory Response Defense Response To Fungus Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Cytoskeleton Organization Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Neutrophil Aggregation Cellular Oxidant Detoxification Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways			RHO GTPases Activate NADPH Oxidases Regulation of TLR by endogenous ligand Neutrophil degranulation Metal sequestration by antimicrobial proteins
Drugs			Calcium Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS			Asthma ( 31619474) Basophil percentage of white cells ( 32888494) Matrix metalloproteinase-8 levels ( 29212897)
Interacting Genes		16 interacting genes: ACOT7 BCL7B C17orf49 CINP DNM1L ENOX2 EXOC5 HLA-DRB1 HTT IQSEC1 KIF27 LSM2 PCYT1A RUSC1 S100A9 STAMBPL1	12 interacting genes: CDC42 EGFR MAGEA1 MAGEA3 MAGEA6 MAPK14 NCF2 PTEN S100A8 S100B TUBA1A TUBB
Entrez ID		4102	6280
HPRD ID		02166	00472
Ensembl ID		ENSG00000221867	ENSG00000163220
Uniprot IDs		P43357	P06702
PDB IDs		1QEW 4V0P 5BRZ	1IRJ 1XK4 4GGF 4XJK 5I8N 5W1F 6DS2
Enriched GO Terms of Interacting Partners?
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