IQSEC1

Description		IQ motif and Sec7 domain ArfGEF 1
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GO Annotations	Cellular Component	Nucleolus Synaptic Vesicle Postsynaptic Density Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding
	Biological Process	Actin Cytoskeleton Organization Regulation Of ARF Protein Signal Transduction Positive Regulation Of GTPase Activity Positive Regulation Of Keratinocyte Migration Dendritic Spine Development Positive Regulation Of Focal Adhesion Disassembly
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Periodontitis (DPAL) ( 24024966) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		2 interacting genes: APOE MAGEA3
Entrez ID		9922
HPRD ID		11052
Ensembl ID		ENSG00000144711
Uniprot IDs		A0A0C4DGT3 B4DGC5 Q6DN90
PDB IDs		3QWM 4C0A 5NLV 5NLY 6FNE
Enriched GO Terms of Interacting Partners?
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