MAGEA3 and EXOC5

Data Source:
BioGRID (two hybrid)

		MAGEA3	EXOC5
Description		MAGE family member A3	exocyst complex component 5
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum	Exocyst Cytoplasm Cytosol Midbody
	Molecular Function	Protein Binding Caspase Binding	Protein Binding Small GTPase Binding
	Biological Process	Negative Regulation Of Protein Processing Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Exocytosis Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Protein Transport
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS			Alcohol consumption ( 23743675) Chronotype ( 30696823) Response to ranibizumab in age-related macular degeneration (exudative) ( 30054556)
Interacting Genes		16 interacting genes: ACOT7 BCL7B C17orf49 CINP DNM1L ENOX2 EXOC5 HLA-DRB1 HTT IQSEC1 KIF27 LSM2 PCYT1A RUSC1 S100A9 STAMBPL1	43 interacting genes: ACTR3B ADCK1 ARF6 BARD1 BRMS1L C1orf216 CCDC102B CDH2 CRYBB1 DEUP1 DNAAF4 EDRF1 ENO2 EXOC6 EXOC6B FGA FRMD6 HDDC3 HGS ICA1 IFT57 KIFC3 KXD1 MAGEA3 MAGEA6 OAS1 PRKCG PSTPIP1 PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 SPACA9 TBX21 THOC1 TNPO2 TTC23L TXLNB TXNL4A USP2
Entrez ID		4102	10640
HPRD ID		02166	07258
Ensembl ID		ENSG00000221867	ENSG00000070367
Uniprot IDs		P43357	O00471
PDB IDs		1QEW 4V0P 5BRZ
Enriched GO Terms of Interacting Partners?
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