TBC1D4 and TASOR

Data Source:
HPRD (two hybrid)

		TBC1D4	TASOR
Description		TBC1 domain family member 4	transcription activation suppressor
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GO Annotations	Cellular Component	Cytosol Vesicle	Heterochromatin Nucleoplasm
	Molecular Function	GTPase Activator Activity Protein Binding	Chromatin Binding RNA Binding Protein Binding
	Biological Process	Intracellular Protein Transport Vesicle-mediated Transport Negative Regulation Of Vesicle Fusion Cellular Response To Insulin Stimulus Activation Of GTPase Activity	In Utero Embryonic Development Anterior/posterior Axis Specification, Embryo Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Mesodermal To Mesenchymal Transition Involved In Gastrulation Mitotic Spindle Assembly Positive Regulation Of DNA Methylation-dependent Heterochromatin Assembly Protein Localization To Heterochromatin
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane
Drugs
Diseases
GWAS		Diabetic retinopathy ( 23562823) Eosinophil counts ( 32888494) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Heart failure ( 20445134) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 29403010 32888494 27863252) Mean platelet volume ( 27863252) Mean reticulocyte volume ( 32888494) Red blood cell count ( 29403010 32888494 27863252) Two-hour glucose ( 25043022) Type 2 diabetes ( 29926116) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		16 interacting genes: AKT1 CDK5RAP2 EP400 FBXW11 LAMTOR5 NAV1 NFAT5 PIN1 RBM12 RESF1 TASOR TET2 TOPBP1 U2SURP YWHAG ZMIZ1	4 interacting genes: AP2M1 RB1 TBC1D4 TOM1L1
Entrez ID		9882	23272
HPRD ID		18164	10183
Ensembl ID		ENSG00000136111	ENSG00000163946
Uniprot IDs		A0A3B3IRT3 O60343	Q9UK61
PDB IDs		3QYB	6SWG 6TL1
Enriched GO Terms of Interacting Partners?
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