TASOR and TBC1D4

Data Source:
HPRD (two hybrid)

		TASOR	TBC1D4
Description		transcription activation suppressor	TBC1 domain family member 4
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GO Annotations	Cellular Component	Heterochromatin Nucleoplasm	Cytosol Vesicle
	Molecular Function	Chromatin Binding RNA Binding Protein Binding	GTPase Activator Activity Protein Binding
	Biological Process	In Utero Embryonic Development Anterior/posterior Axis Specification, Embryo Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Mesodermal To Mesenchymal Transition Involved In Gastrulation Mitotic Spindle Assembly Positive Regulation Of DNA Methylation-dependent Heterochromatin Assembly Protein Localization To Heterochromatin	Intracellular Protein Transport Vesicle-mediated Transport Negative Regulation Of Vesicle Fusion Cellular Response To Insulin Stimulus Activation Of GTPase Activity
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane
Drugs
Diseases
GWAS			Diabetic retinopathy ( 23562823) Eosinophil counts ( 32888494) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Heart failure ( 20445134) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 29403010 32888494 27863252) Mean platelet volume ( 27863252) Mean reticulocyte volume ( 32888494) Red blood cell count ( 29403010 32888494 27863252) Two-hour glucose ( 25043022) Type 2 diabetes ( 29926116) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		4 interacting genes: AP2M1 RB1 TBC1D4 TOM1L1	16 interacting genes: AKT1 CDK5RAP2 EP400 FBXW11 LAMTOR5 NAV1 NFAT5 PIN1 RBM12 RESF1 TASOR TET2 TOPBP1 U2SURP YWHAG ZMIZ1
Entrez ID		23272	9882
HPRD ID		10183	18164
Ensembl ID		ENSG00000163946	ENSG00000136111
Uniprot IDs		Q9UK61	A0A3B3IRT3 O60343
PDB IDs		6SWG 6TL1	3QYB
Enriched GO Terms of Interacting Partners?
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