ZC3H11A and RAPGEF4

Data Source:
BioGRID (two hybrid)

		ZC3H11A	RAPGEF4
Description		zinc finger CCCH-type containing 11A	Rap guanine nucleotide exchange factor 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Transcription Export Complex Nucleoplasm	Cytosol Plasma Membrane Membrane Hippocampal Mossy Fiber To CA3 Synapse
	Molecular Function	RNA Binding MRNA Binding Protein Binding Metal Ion Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding CAMP Binding Small GTPase Binding
	Biological Process	RNA Export From Nucleus MRNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus MRNA 3'-end Processing	G Protein-coupled Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Calcium-ion Regulated Exocytosis Regulation Of Exocytosis CAMP-mediated Signaling Insulin Secretion Regulation Of Catalytic Activity Regulation Of Insulin Secretion Regulation Of Synaptic Vesicle Cycle
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination	Integrin signaling Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Rap1 signalling Regulation of insulin secretion
Drugs
Diseases
GWAS		Breast cancer ( 25038754) Male-pattern baldness ( 28196072)	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Fasting plasma glucose ( 25187374) GLP-1 levels in response to oral glucose tolerance test (fasting) ( 29093273) HDL cholesterol levels ( 32203549) Hippocampal volume ( 25625606) Lateral ventricle temporal horn volume ( 31530798)
Interacting Genes		9 interacting genes: MIR141 MIR214 MIR9-1 MIR9-2 MLH1 MTNR1A RAPGEF4 SMARCB1 SUMO2	13 interacting genes: ATXN1 BMERB1 DEF6 LRRK2 MAP1A RAP1A RAP2A RIMS2 RRAS2 SWAP70 TRAF2 TSPOAP1 ZC3H11A
Entrez ID		9877	11069
HPRD ID		11100	06929
Ensembl ID		ENSG00000058673	ENSG00000091428
Uniprot IDs		O75152	B7Z278 Q8WZA2
PDB IDs
Enriched GO Terms of Interacting Partners?
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