TLK1 and ASF1B

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		TLK1	ASF1B
Description		tousled like kinase 1	anti-silencing function 1B histone chaperone
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Chromatin Nucleoplasm Protein-containing Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Binding Histone Binding
	Biological Process	Regulation Of Chromatin Assembly Or Disassembly Chromatin Organization Protein Phosphorylation Intracellular Protein Transport Cellular Response To DNA Damage Stimulus Cell Cycle Chromosome Segregation Peptidyl-serine Phosphorylation Intracellular Signal Transduction	Blastocyst Hatching DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Spermatogenesis Cell Differentiation
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Health literacy ( 31250787) Menopause (age at onset) ( 22267201 26414677) Platelet distribution width ( 32888494 27863252)
Interacting Genes		28 interacting genes: ASF1A ASF1B AURKA BEND7 BHLHB9 CHEK1 DPPA4 DYNLL2 H1-1 LHX2 LUZP4 MBP NBN PAX6 PINX1 PTPN11 RAD9A SNAP23 TFCP2 TLK2 TPM3 UBE3C YAF2 YWHAE ZNF655 ZNF773 ZNF829 ZSCAN22	13 interacting genes: ASF1A CDIN1 CHAF1A CHAF1B H3-3A H3C3 H3C6 H4-16 H4C6 HCFC1 TAF1 TLK1 TLK2
Entrez ID		9874	55723
HPRD ID		12232	16460
Ensembl ID		ENSG00000198586	ENSG00000105011
Uniprot IDs		Q9UKI8	A0A024R7G4 Q9NVP2
PDB IDs			5BNX 5BO0
Enriched GO Terms of Interacting Partners?
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