ASF1B and TLK2

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		ASF1B	TLK2
Description		anti-silencing function 1B histone chaperone	tousled like kinase 2
Image
GO Annotations	Cellular Component	Chromatin Nucleoplasm Protein-containing Complex	Nucleus Intermediate Filament Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Histone Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Identical Protein Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Blastocyst Hatching DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Spermatogenesis Cell Differentiation	Regulation Of Chromatin Assembly Or Disassembly Chromatin Organization Protein Phosphorylation Cellular Response To DNA Damage Stimulus Cell Cycle Chromosome Segregation Negative Regulation Of Autophagy Peptidyl-serine Phosphorylation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Cellular Response To Gamma Radiation
Pathways
Drugs			Fostamatinib
Diseases
GWAS			Heel bone mineral density ( 30598549) Lifespan ( 25918517)
Interacting Genes		13 interacting genes: ASF1A CDIN1 CHAF1A CHAF1B H3-3A H3C3 H3C6 H4-16 H4C6 HCFC1 TAF1 TLK1 TLK2	17 interacting genes: ASF1A ASF1B AURKA CEP70 DMAP1 FEZ1 FEZ2 FRMD6 GMCL1 IRF4 IRF7 MBP PAX5 PAX6 TLK1 UBE2I YWHAZ
Entrez ID		55723	11011
HPRD ID		16460	10527
Ensembl ID		ENSG00000105011	ENSG00000146872
Uniprot IDs		A0A024R7G4 Q9NVP2	B4DUC2 J3QLK5 Q86UE8
PDB IDs		5BNX 5BO0	5O0Y
Enriched GO Terms of Interacting Partners?
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