RNF40 and SFR1

Data Source:
BioGRID (two hybrid)

		RNF40	SFR1
Description		ring finger protein 40	SWI5 dependent homologous recombination repair protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytosol Membrane Extrinsic Component Of Membrane HULC Complex Neuron Projection Axon Terminus	Nucleus Swi5-Sfr1 Complex
	Molecular Function	MRNA 3'-UTR Binding Ubiquitin-protein Transferase Activity Protein Binding Syntaxin-1 Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Protein-containing Complex Binding Metal Ion Binding	Protein Binding Nuclear Receptor Coactivator Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Cell Cycle Histone Monoubiquitination Protein Ubiquitination Histone H2B Ubiquitination Response To Peptide Hormone Negative Regulation Of MRNA Polyadenylation Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Polyubiquitination Positive Regulation Of Histone H2B Ubiquitination	Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Transcription, DNA-templated Cellular Response To Estrogen Stimulus
Pathways		E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Immunoglobulin light chain (AL) amyloidosis ( 28025584)
Interacting Genes		26 interacting genes: AMOTL2 ATM CCDC146 CDC73 DISC1 DUSP29 EEF1D ITSN1 KIF11 MEOX2 MSL1 MTNR1B NCBP1 NINL RB1 RNF20 SFR1 TRIM51 UBE2A UBE2B UBE2D2 UBE2E1 UBE2I UBE2L6 ZCCHC12 ZNF451	15 interacting genes: CDC5L CEP70 DTNBP1 EXOC1 FBXO7 HMBOX1 MRFAP1L1 NDC80 NMI RAD51 RINT1 RNF40 SWI5 TFIP11 TRAF3IP1
Entrez ID		9810	119392
HPRD ID		07411	12590
Ensembl ID		ENSG00000103549	ENSG00000156384
Uniprot IDs		A8K6K1 O75150	Q86XK3
PDB IDs
Enriched GO Terms of Interacting Partners?
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