SFR1 and EXOC1

Data Source:
BioGRID (two hybrid)

		SFR1	EXOC1
Description		SWI5 dependent homologous recombination repair protein 1	exocyst complex component 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Swi5-Sfr1 Complex	Exocyst Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Flemming Body Cytoplasmic Side Of Apical Plasma Membrane
	Molecular Function	Protein Binding Nuclear Receptor Coactivator Activity	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Transcription, DNA-templated Cellular Response To Estrogen Stimulus	Exocytosis Golgi To Plasma Membrane Transport Protein Transport Viral Process Regulation Of Macroautophagy Phosphatidylinositol-mediated Signaling Positive Regulation Of Protein Secretion Defense Response To Virus
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS			Cerebrospinal P-tau181p levels ( 28247064) Cervical cancer ( 23817570) Daytime sleep phenotypes ( 27126917) Urinary albumin excretion ( 32277301) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		15 interacting genes: CDC5L CEP70 DTNBP1 EXOC1 FBXO7 HMBOX1 MRFAP1L1 NDC80 NMI RAD51 RINT1 RNF40 SWI5 TFIP11 TRAF3IP1	30 interacting genes: ATG14 CCDC88A CCDC93 CCHCR1 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST KANSL1 KDM1A LUC7L2 MACF1 MTNR1A NUF2 NUP54 RALA RB1CC1 RESF1 RUBCN SFR1 SH3BP5 SNAPIN SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIM9 TRIO
Entrez ID		119392	55763
HPRD ID		12590	07615
Ensembl ID		ENSG00000156384	ENSG00000090989
Uniprot IDs		Q86XK3	A0A024RDA1 A1LT29 Q9NV70
PDB IDs
Enriched GO Terms of Interacting Partners?
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