RNF40 and TRIM51

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RNF40	TRIM51
Description		ring finger protein 40	tripartite motif-containing 51
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytosol Membrane Extrinsic Component Of Membrane HULC Complex Neuron Projection Axon Terminus	Cytoplasm
	Molecular Function	MRNA 3'-UTR Binding Ubiquitin-protein Transferase Activity Protein Binding Syntaxin-1 Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Protein-containing Complex Binding Metal Ion Binding	Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Cell Cycle Histone Monoubiquitination Protein Ubiquitination Histone H2B Ubiquitination Response To Peptide Hormone Negative Regulation Of MRNA Polyadenylation Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Polyubiquitination Positive Regulation Of Histone H2B Ubiquitination	Regulation Of Gene Expression Protein Ubiquitination Innate Immune Response
Pathways		E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Immunoglobulin light chain (AL) amyloidosis ( 28025584)	Attention deficit hyperactivity disorder ( 30563984) Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		26 interacting genes: AMOTL2 ATM CCDC146 CDC73 DISC1 DUSP29 EEF1D ITSN1 KIF11 MEOX2 MSL1 MTNR1B NCBP1 NINL RB1 RNF20 SFR1 TRIM51 UBE2A UBE2B UBE2D2 UBE2E1 UBE2I UBE2L6 ZCCHC12 ZNF451	3 interacting genes: MAGEA11 RNF40 SPRY2
Entrez ID		9810	84767
HPRD ID		07411	10282
Ensembl ID		ENSG00000103549	ENSG00000124900
Uniprot IDs		A8K6K1 O75150	Q9BSJ1
PDB IDs
Enriched GO Terms of Interacting Partners?
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