CD81 and BST2

Data Source:
BioGRID (two hybrid)

		CD81	BST2
Description		CD81 molecule	bone marrow stromal cell antigen 2
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GO Annotations	Cellular Component	Immunological Synapse Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Basal Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Vesicle Extracellular Exosome Tetraspanin-enriched Microdomain	Cytoplasm Multivesicular Body Golgi Apparatus Cytosol Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Apical Plasma Membrane Anchored Component Of Membrane Azurophil Granule Membrane Membrane Raft Extracellular Exosome
	Molecular Function	Virus Receptor Activity Integrin Binding Protein Binding Cholesterol Binding MHC Class II Protein Complex Binding MHC Class II Protein Binding Transferrin Receptor Binding	RNA Binding Protein Binding Metalloendopeptidase Inhibitor Activity Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Activation Of MAPK Activity Immunological Synapse Formation Humoral Immune Response Mediated By Circulating Immunoglobulin Positive Regulation Of Inflammatory Response To Antigenic Stimulus Protein Localization Positive Regulation Of Cell Population Proliferation Myoblast Fusion Involved In Skeletal Muscle Regeneration Regulation Of Complement Activation Positive Regulation Of B Cell Proliferation Receptor Internalization Regulation Of Protein Stability Macrophage Fusion CD4-positive, Alpha-beta T Cell Costimulation Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Positive Regulation Of Transcription By RNA Polymerase II Viral Entry Into Host Cell Receptor-mediated Virion Attachment To Host Cell Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Immune Response Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of T Cell Receptor Signaling Pathway Protein Localization To Lysosome Positive Regulation Of Protein Exit From Endoplasmic Reticulum Cellular Response To Low-density Lipoprotein Particle Stimulus Protein Localization To Plasma Membrane Osteoclast Fusion Positive Regulation Of Receptor Clustering Positive Regulation Of Protein Catabolic Process In The Vacuole Regulation Of Macrophage Migration Positive Regulation Of Adaptive Immune Memory Response Positive Regulation Of T-helper 2 Cell Cytokine Production Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell	Negative Regulation Of Plasmacytoid Dendritic Cell Cytokine Production Response To Virus Negative Regulation Of Endopeptidase Activity Negative Regulation Of Cell Growth Negative Regulation Of Cell Migration Regulation Of Actin Cytoskeleton Organization Response To Interferon-gamma Response To Interferon-alpha Response To Interferon-beta B Cell Activation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Neutrophil Degranulation Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Type I Interferon Signaling Pathway Positive Regulation Of Leukocyte Proliferation Negative Regulation Of Intracellular Transport Of Viral Material
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Regulation of Complement cascade	Neutrophil degranulation Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Malaria ( 31844061)
Interacting Genes		58 interacting genes: ADRA1A ADRB2 AQP6 BDKRB2 BST2 CCR2 CCR9 CD19 CD9 CHRM4 CPLX4 CSNK2B DLG5 EBP ERGIC3 F2RL1 FAM209A GJA4 GLP1R GORAB GPR152 GPR35 GPX8 HNRNPD HRH1 HTR4 IFITM1 IGSF8 INO80B ITGA4 JAK3 KIT LBR LHFPL5 LMNA MC4R MCEE MRPS18B MYOC NEMP1 OXTR PDZK1IP1 PTGFRN RBBP6 RNF128 SAR1A SDHAF4 SHC1 SIRPA SLC26A6 STX1A THAP4 TMX2 TREX1 TSHR TSPAN4 VKORC1 ZBTB16	3 interacting genes: CD81 HAGH HARS2
Entrez ID		975	684
HPRD ID		08924	02759
Ensembl ID		ENSG00000110651	ENSG00000130303
Uniprot IDs		A0A024RCB7 E9PJK1 P60033	A0A024R7H5 Q10589
PDB IDs		1G8Q 1IV5 2AVZ 3X0E 5DFV 5DFW 5M2C 5M33 5M3D 5M3T 5M4R 5TCX 6EJG 6EJM 6EK2 6U9S	2LK9 2X7A 2XG7 3MQ7 3MQ9 3MQB 3MQC 3NWH 4P6Z 6CM9 6CRI 6D83 6D84 6DFF
Enriched GO Terms of Interacting Partners?
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