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CD81 and PTGFRN
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology, affinity chromatography technology)
HPRD
(in vivo, in vitro)
CD81
PTGFRN
Description
CD81 molecule
prostaglandin F2 receptor inhibitor
Image
No pdb structure
GO Annotations
Cellular Component
Immunological Synapse
Plasma Membrane
Integral Component Of Plasma Membrane
Focal Adhesion
Basal Plasma Membrane
Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Vesicle
Extracellular Exosome
Tetraspanin-enriched Microdomain
Endoplasmic Reticulum Membrane
Golgi Apparatus
Cell Surface
Integral Component Of Membrane
Molecular Function
Virus Receptor Activity
Integrin Binding
Protein Binding
Cholesterol Binding
MHC Class II Protein Complex Binding
MHC Class II Protein Binding
Transferrin Receptor Binding
Protein Binding
Biological Process
Activation Of MAPK Activity
Immunological Synapse Formation
Humoral Immune Response Mediated By Circulating Immunoglobulin
Positive Regulation Of Inflammatory Response To Antigenic Stimulus
Protein Localization
Positive Regulation Of Cell Population Proliferation
Myoblast Fusion Involved In Skeletal Muscle Regeneration
Regulation Of Complement Activation
Positive Regulation Of B Cell Proliferation
Receptor Internalization
Regulation Of Protein Stability
Macrophage Fusion
CD4-positive, Alpha-beta T Cell Costimulation
Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity
Positive Regulation Of Transcription By RNA Polymerase II
Viral Entry Into Host Cell
Receptor-mediated Virion Attachment To Host Cell
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Regulation Of Immune Response
Positive Regulation Of B Cell Receptor Signaling Pathway
Positive Regulation Of T Cell Receptor Signaling Pathway
Protein Localization To Lysosome
Positive Regulation Of Protein Exit From Endoplasmic Reticulum
Cellular Response To Low-density Lipoprotein Particle Stimulus
Protein Localization To Plasma Membrane
Osteoclast Fusion
Positive Regulation Of Receptor Clustering
Positive Regulation Of Protein Catabolic Process In The Vacuole
Regulation Of Macrophage Migration
Positive Regulation Of Adaptive Immune Memory Response
Positive Regulation Of T-helper 2 Cell Cytokine Production
Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell
Myoblast Fusion Involved In Skeletal Muscle Regeneration
Lipid Droplet Organization
Pathways
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Regulation of Complement cascade
Drugs
Diseases
GWAS
Malaria (
31844061
)
Blood protein levels (
30072576
29875488
)
Erectile dysfunction and prostate cancer treatment (
20932654
)
Gout (normal type) (
32238385
)
Low susceptibility to hepatitis C infection (
31206233
)
T-Cell Immunoglobulin and Mucin domain 1 levels (
32460577
)
Type 2 diabetes (
30054458
30297969
)
Interacting Genes
58 interacting genes:
ADRA1A
ADRB2
AQP6
BDKRB2
BST2
CCR2
CCR9
CD19
CD9
CHRM4
CPLX4
CSNK2B
DLG5
EBP
ERGIC3
F2RL1
FAM209A
GJA4
GLP1R
GORAB
GPR152
GPR35
GPX8
HNRNPD
HRH1
HTR4
IFITM1
IGSF8
INO80B
ITGA4
JAK3
KIT
LBR
LHFPL5
LMNA
MC4R
MCEE
MRPS18B
MYOC
NEMP1
OXTR
PDZK1IP1
PTGFRN
RBBP6
RNF128
SAR1A
SDHAF4
SHC1
SIRPA
SLC26A6
STX1A
THAP4
TMX2
TREX1
TSHR
TSPAN4
VKORC1
ZBTB16
5 interacting genes:
CD151
CD63
CD81
CD82
CD9
Entrez ID
975
5738
HPRD ID
08924
03124
Ensembl ID
ENSG00000110651
ENSG00000134247
Uniprot IDs
A0A024RCB7
E9PJK1
P60033
Q9P2B2
PDB IDs
1G8Q
1IV5
2AVZ
3X0E
5DFV
5DFW
5M2C
5M33
5M3D
5M3T
5M4R
5TCX
6EJG
6EJM
6EK2
6U9S
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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