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AQR and MIRLET7E
Data Source:
BioGRID
(unspecified method)
AQR
MIRLET7E
Description
aquarius intron-binding spliceosomal factor
microRNA let-7e
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Membrane
U2-type Catalytic Step 2 Spliceosome
Catalytic Step 2 Spliceosome
Extracellular Space
Molecular Function
RNA Binding
Single-stranded RNA Binding
MRNA Binding
Protein Binding
ATP Binding
3'-5' RNA Helicase Activity
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
MRNA Splicing, Via Spliceosome
Transcription-coupled Nucleotide-excision Repair
Negative Regulation Of Interleukin-6 Production
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein
Negative Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of Interleukin-6-mediated Signaling Pathway
Negative Regulation Of Receptor Signaling Pathway Via STAT
Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Negative Regulation Of Signaling Receptor Activity
Pathways
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Interacting Genes
40 interacting genes:
MIR1-1
MIR106A
MIR106B
MIR107
MIR128-2
MIR145
MIR15B
MIR199A2
MIR19B1
MIR19B2
MIR200B
MIR200C
MIR205
MIR206
MIR20B
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR31
MIR34A
MIR34B
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR92A2
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7D
MIRLET7E
MIRLET7G
MIRLET7I
PQBP1
RBM22
RBM4
WDR77
105 interacting genes:
AIMP1
AIMP2
APOBEC3B
AQR
ATXN2L
C1QBP
CDC40
CDC5L
CELF1
CHERP
CPSF1
CRTAP
DARS1
DDX1
DDX21
DDX23
DDX3X
DHX36
DHX37
EDC4
EIF2AK2
EPRS1
ERAL1
FAM98A
FAM98B
FUS
G3BP2
GRSF1
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT16L1
NUDT21
NUFIP2
PDCD11
PGAM5
PLOD1
PLRG1
PRMT1
PTBP1
PUF60
PUM1
PUM2
PURA
QARS1
RARS1
RBFOX2
RBM10
RBM14
RBM4
RBM47
RBM5
RTCB
SART3
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SUGP2
SYMPK
SYNCRIP
TAF15
TRA2A
TRA2B
TUT7
U2SURP
UPF1
UTP20
XAB2
YBX1
YBX2
YBX3
ZFR
ZNF346
Entrez ID
9716
406887
HPRD ID
12468
Ensembl ID
ENSG00000021776
ENSG00000198972
Uniprot IDs
A0A024R9L1
O60306
PDB IDs
4PJ3
5MQF
5XJC
5YZG
5Z56
5Z57
6FF7
6ICZ
6ID0
6ID1
6QDV
7A5P
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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