AQR and RBM22

Data Source:
BioGRID (two hybrid, two hybrid)

		AQR	RBM22
Description		aquarius intron-binding spliceosomal factor	RNA binding motif protein 22
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Membrane U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Prp19 Complex Nucleus Nucleoplasm Cytoplasm U2-type Catalytic Step 1 Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding ATP Binding 3'-5' RNA Helicase Activity	RNA Binding Protein Binding U6 SnRNA Binding Pre-mRNA Binding Metal Ion Binding Calcium-dependent Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription-coupled Nucleotide-excision Repair	MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing Cellular Response To Drug Positive Regulation Of Protein Import Into Nucleus MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Protein Export From Nucleus
Pathways		Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)
Interacting Genes		40 interacting genes: MIR1-1 MIR106A MIR106B MIR107 MIR128-2 MIR145 MIR15B MIR199A2 MIR19B1 MIR19B2 MIR200B MIR200C MIR205 MIR206 MIR20B MIR214 MIR221 MIR222 MIR25 MIR29A MIR31 MIR34A MIR34B MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR92A2 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7D MIRLET7E MIRLET7G MIRLET7I PQBP1 RBM22 RBM4 WDR77	14 interacting genes: AQR CEP55 CYSRT1 GIGYF1 GOLGA2 HNRNPUL1 HOMER3 NCKIPSD PRNP RBFOX2 RBM4 RNU6-1 RNU6-50P RNU6-6P
Entrez ID		9716	55696
HPRD ID		12468	10186
Ensembl ID		ENSG00000021776	ENSG00000086589
Uniprot IDs		A0A024R9L1 O60306	Q9NW64
PDB IDs		4PJ3 5MQF 5XJC 5YZG 5Z56 5Z57 6FF7 6ICZ 6ID0 6ID1 6QDV 7A5P	2YTC 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
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