MIRLET7E and TUT7

Data Source:
BioGRID (unspecified method)

		MIRLET7E	TUT7
Description		microRNA let-7e	terminal uridylyl transferase 7
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding Protein Binding Zinc Ion Binding Nucleotidyltransferase Activity MiRNA Binding RNA Uridylyltransferase Activity Uridylyltransferase Activity
	Biological Process	Negative Regulation Of Interleukin-6 Production Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Interleukin-6-mediated Signaling Pathway Negative Regulation Of Receptor Signaling Pathway Via STAT Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Negative Regulation Of Signaling Receptor Activity	Nuclear-transcribed MRNA Poly(A) Tail Shortening Oocyte Maturation Negative Regulation Of Transposition, RNA-mediated MiRNA Metabolic Process Pre-miRNA Processing RNA 3'-end Processing Histone MRNA Catabolic Process RNA 3' Uridylation Polyuridylation-dependent MRNA Catabolic Process
Pathways			Deadenylation of mRNA
Drugs
Diseases
GWAS
Interacting Genes		105 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CDC40 CDC5L CELF1 CHERP CPSF1 CRTAP DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FAM98B FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PGAM5 PLOD1 PLRG1 PRMT1 PTBP1 PUF60 PUM1 PUM2 PURA QARS1 RARS1 RBFOX2 RBM10 RBM14 RBM4 RBM47 RBM5 RTCB SART3 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TUT7 U2SURP UPF1 UTP20 XAB2 YBX1 YBX2 YBX3 ZFR ZNF346	14 interacting genes: APP MIR138-2 MIR25 MIRLET7A1 MIRLET7A2 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I ZDHHC17
Entrez ID		406887	79670
HPRD ID			11697
Ensembl ID		ENSG00000198972	ENSG00000083223
Uniprot IDs			Q5VYS8 Q96KX5 X6R3Q3
PDB IDs			5W0B 5W0M 5W0N 5W0O
Enriched GO Terms of Interacting Partners?
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