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AQR and MIR214
Data Source:
BioGRID
(unspecified method)
AQR
MIR214
Description
aquarius intron-binding spliceosomal factor
microRNA 214
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Membrane
U2-type Catalytic Step 2 Spliceosome
Catalytic Step 2 Spliceosome
Nucleus
Perinuclear Region Of Cytoplasm
Extracellular Vesicle
Molecular Function
RNA Binding
Single-stranded RNA Binding
MRNA Binding
Protein Binding
ATP Binding
3'-5' RNA Helicase Activity
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
MRNA Splicing, Via Spliceosome
Transcription-coupled Nucleotide-excision Repair
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Lamellipodium Assembly
Negative Regulation Of Gene Expression
Negative Regulation Of Angiogenesis
Negative Regulation Of Cell Migration
Negative Regulation Of Actin Filament Polymerization
Gene Silencing By MiRNA
Negative Regulation Of Necroptotic Process
Cellular Response To Hypoxia
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Positive Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation
Positive Regulation Of Connective Tissue Replacement
Pathways
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Height (
31562340
)
Interacting Genes
40 interacting genes:
MIR1-1
MIR106A
MIR106B
MIR107
MIR128-2
MIR145
MIR15B
MIR199A2
MIR19B1
MIR19B2
MIR200B
MIR200C
MIR205
MIR206
MIR20B
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR31
MIR34A
MIR34B
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR92A2
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7D
MIRLET7E
MIRLET7G
MIRLET7I
PQBP1
RBM22
RBM4
WDR77
92 interacting genes:
AIMP1
AIMP2
AQR
ATXN2L
C1QBP
CDC5L
CELF1
CPSF1
DARS1
DDX1
DDX21
DDX23
DDX3X
DDX49
DHX36
DHX37
EDC4
EIF2AK2
EPRS1
ERAL1
FAM98A
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LRPPRC
MARS1
MATR3
MSI2
NOL6
NONO
NUDT21
NUFIP2
PDCD11
PGAM5
PLOD1
PTBP1
PTCD3
PUF60
PUM1
PUM2
QARS1
RARS1
RBFOX2
RBM10
RBM14
RBM4
RBM4B
RTCA
RTCB
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SFPQ
SPOUT1
STRBP
SUGP2
SYMPK
SYNCRIP
TAF15
TRA2A
TRA2B
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZC3H11A
ZFR
ZNF346
Entrez ID
9716
406996
HPRD ID
12468
Ensembl ID
ENSG00000021776
ENSG00000283844
Uniprot IDs
A0A024R9L1
O60306
PDB IDs
4PJ3
5MQF
5XJC
5YZG
5Z56
5Z57
6FF7
6ICZ
6ID0
6ID1
6QDV
7A5P
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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