CD70 and CD27

Data Source:
HPRD (in vivo)

		CD70	CD27
Description		CD70 molecule	CD27 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Protease Binding Signaling Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding	Transmembrane Signaling Receptor Activity Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
	Biological Process	T Cell Mediated Immunity Signal Transduction Cell-cell Signaling B Cell Mediated Immunity Tumor Necrosis Factor-mediated Signaling Pathway B Cell Proliferation Positive Regulation Of T Cell Proliferation Extrinsic Apoptotic Signaling Pathway	Cell Surface Receptor Signaling Pathway Immunoglobulin Mediated Immune Response Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Response To Ethanol Positive Regulation Of B Cell Differentiation Positive Regulation Of T Cell Differentiation Positive Regulation Of JNK Cascade Negative Regulation Of T Cell Apoptotic Process Extrinsic Apoptotic Signaling Pathway Positive Regulation Of NIK/NF-kappaB Signaling
Pathways		TNFs bind their physiological receptors	TNFs bind their physiological receptors
Drugs
Diseases
GWAS		Asthma ( 32296059)	Crohn's disease ( 26192919)
Interacting Genes		2 interacting genes: CD27 ELOVL4	8 interacting genes: ACTN2 CD70 CIB1 SIVA1 TRAF2 TRAF3 TRAF5 UHRF2
Entrez ID		970	939
HPRD ID		18515	01723
Ensembl ID		ENSG00000125726	ENSG00000139193
Uniprot IDs		A0A0U5JA32 P32970	P26842
PDB IDs			5TL5 5TLJ 5TLK
Enriched GO Terms of Interacting Partners?
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