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CD27
Description
CD27 molecule
Image
GO Annotations
Cellular Component
Extracellular Region
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Molecular Function
Transmembrane Signaling Receptor Activity
Protein Binding
Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
Biological Process
Cell Surface Receptor Signaling Pathway
Immunoglobulin Mediated Immune Response
Tumor Necrosis Factor-mediated Signaling Pathway
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Ethanol
Positive Regulation Of B Cell Differentiation
Positive Regulation Of T Cell Differentiation
Positive Regulation Of JNK Cascade
Negative Regulation Of T Cell Apoptotic Process
Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of NIK/NF-kappaB Signaling
Pathways
TNFs bind their physiological receptors
Drugs
Diseases
GWAS
Crohn's disease (
26192919
)
Novel Interacting Genes
6 novel interacting genes:
CCND2
CHD4
CREBL2
ELF1
ENO2
ETV6
Interacting Genes
8 interacting genes:
ACTN2
CD70
CIB1
SIVA1
TRAF2
TRAF3
TRAF5
UHRF2
Entrez ID
939
HPRD ID
01723
Ensembl ID
ENSG00000139193
Uniprot IDs
P26842
PDB IDs
5TL5
5TLJ
5TLK
Enriched GO Terms of Interacting Partners
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