IPO13 and MAST2

Data Source:
BioGRID (biochemical)

		IPO13	MAST2
Description		importin 13	microtubule associated serine/threonine kinase 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Plasma Membrane Microtubule Cytoskeleton
	Molecular Function	Protein Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding Phosphatase Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Protein Import Into Nucleus	Protein Phosphorylation Cytoskeleton Organization Peptidyl-serine Phosphorylation Regulation Of Interleukin-12 Production Intracellular Signal Transduction Spermatid Differentiation
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026)	Blood protein levels ( 28240269) Body mass index ( 25673413) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Granulocyte count ( 27863252) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Iron status biomarkers (total iron binding capacity) ( 28334935) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Red blood cell count ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Sum basophil neutrophil counts ( 27863252) Type 2 diabetes ( 32499647)
Interacting Genes		17 interacting genes: ALX1 CRX EIF1AX GK HMBOX1 MAGOH NPSR1 NUP50 PAX3 PAX6 PBX4 PITX1 PSMA1 RAN RBM8A RPL5 UBE2I	24 interacting genes: ACTN2 APP CDHR2 DYNLL1 MXRA7 PTEN RPS27A RPS6KA1 SH3GL2 SLC34A1 SLC9A3 SMN1 SNTB2 SRPK2 STK36 SUMO2 TK1 TPM1 TPM2 TPM3 TRAF2 TRAF6 TTN ZNF417
Entrez ID		9670	23139
HPRD ID		13742	11294
Ensembl ID		ENSG00000117408	ENSG00000086015
Uniprot IDs		O94829	A0A669KBJ4 Q6P0Q8
PDB IDs		2X19 2XWU 3ZJY	2KQF 2KYL
Enriched GO Terms of Interacting Partners?
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