MRPL38 and RALY

Data Source:
BioGRID (two hybrid)

		MRPL38	RALY
Description		mitochondrial ribosomal protein L38	RALY heterogeneous nuclear ribonucleoprotein
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit	Nucleus Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding	Transcription Coregulator Activity RNA Binding Protein Binding
	Biological Process	Mitochondrial Translational Elongation Mitochondrial Translational Termination	MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated Cholesterol Homeostasis Regulation Of Nucleic Acid-templated Transcription
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS			Adult body size ( 32376654) Basal cell carcinoma ( 31174203 27539887) Blond vs. brown/black hair color ( 30531825) Breast cancer ( 22976474) Cancer ( 27197191) Cancer (pleiotropy) ( 27197191) Cutaneous malignant melanoma ( 32341527) Cutaneous squamous cell carcinoma ( 32041948) Estimated glomerular filtration rate ( 31451708) Facial pigmentation ( 25705849) Hair color ( 29662168) HDL cholesterol levels ( 32203549) Idiopathic dilated cardiomyopathy ( 29495422) Keratinocyte cancer (MTAG) ( 31174203) Low tan response ( 29739929) Melanoma ( 28212542) Nevus count or cutaneous melanoma ( 32341527) Non-melanoma skin cancer ( 29739929) Red cell distribution width ( 32888494) Red vs. brown/black hair color ( 30531825) Refractive error ( 32231278) Skin colour saturation ( 25963972) Skin sensitivity to sun ( 25963972) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Squamous cell carcinoma ( 26829030) Type 2 diabetes ( 30297969) Vitiligo ( 27723757) Weight ( 28552196) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		21 interacting genes: ARHGAP9 BAG3 BEX2 CCDC120 CENATAC CSNK2A1 DOCK8 ENKD1 ERCC6 ERG28 GADD45GIP1 GOLGA6A HSPB3 LONRF1 MKRN3 MRPL18 MYOZ3 PPP1R18 PRIM1 RALY TSEN54	31 interacting genes: BCCIP BYSL CELF1 EXOC7 GTPBP3 HNRNPC HNRNPCL1 HNRNPD HNRNPH1 HNRNPK HSF2BP KHDRBS1 LNX1 MRPL38 MTUS2 PCBP1 PIK3CD PLOD3 QKI RALYL RBPMS2 RPL9 SDCBP SKA2 SPG7 THAP1 TIGD3 WDR62 ZBTB24 ZNF408 ZNF76
Entrez ID		64978	22913
HPRD ID		14758	11480
Ensembl ID		ENSG00000204316	ENSG00000125970
Uniprot IDs		Q96DV4	Q53GL6 Q9UKM9
PDB IDs		3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG	1WF1
Enriched GO Terms of Interacting Partners?
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