RPH3AL and RAB3B

Data Source:
HPRD (in vivo, in vitro)

		RPH3AL	RAB3B
Description		rabphilin 3A like (without C2 domains)	RAB3B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Transport Vesicle Membrane Secretory Granule Membrane	Cytoplasm Endosome Golgi Apparatus Cytosol Plasma Membrane Synaptic Vesicle Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome Dopaminergic Synapse Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	Protein Binding Cytoskeletal Protein Binding LIM Domain Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding
	Biological Process	Intracellular Protein Transport Exocytosis Regulation Of Exocytosis Response To Drug Positive Regulation Of Protein Secretion	Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Antigen Processing And Presentation Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Protein Localization To Plasma Membrane Regulation Of Vesicle Size Regulation Of Synaptic Vesicle Cycle
Pathways			RAB geranylgeranylation
Drugs
Diseases
GWAS		AIDS progression ( 21502085) Dimensional psychopathology (Cognitive) ( 29496196) Idiopathic intracranial hypertension ( 29608535) Impaired insulin sensitivity in response to n-3 PUFA supplementation ( 31779001)	Mean platelet volume ( 32888494)
Interacting Genes		25 interacting genes: ANKRD11 ATPAF2 C1orf109 HNRNPK KHDRBS3 MID2 MYO15B PNMA3 PRKAB2 PSME3 RAB27A RAB27B RAB3A RAB3B RAB3C RAB3D RAB3GAP1 RAB8A RIMS2 RSPH14 SAAL1 SCNM1 TCEA3 UNC13B ZYX	16 interacting genes: ACVR1 CALM1 CALM2 CALM3 CHM GDI1 PIGR RABIF RIMS2 RPH3A RPH3AL SGSM2 SMAD1 SMAD4 TGFBR1 VRTN
Entrez ID		9501	5865
HPRD ID		05345	01540
Ensembl ID		ENSG00000181031	ENSG00000169213
Uniprot IDs		A8K7D5 Q9UNE2	P20337
PDB IDs			3DZ8
Enriched GO Terms of Interacting Partners?
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