RAB3B and RPH3A

Data Source:
HPRD (in vitro)

		RAB3B	RPH3A
Description		RAB3B, member RAS oncogene family	rabphilin 3A
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Golgi Apparatus Cytosol Plasma Membrane Synaptic Vesicle Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome Dopaminergic Synapse Anchored Component Of Synaptic Vesicle Membrane	Golgi Apparatus Cytosol Synaptic Vesicle Extrinsic Component Of Membrane Secretory Granule Synaptic Vesicle Membrane Protein-containing Complex Neuron Projection Dendritic Spine Synapse Postsynaptic Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Zinc Ion Binding Selenium Binding Phosphate Ion Binding Protein-containing Complex Binding Inositol 1,4,5 Trisphosphate Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Antigen Processing And Presentation Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Protein Localization To Plasma Membrane Regulation Of Vesicle Size Regulation Of Synaptic Vesicle Cycle	Intracellular Protein Transport Spontaneous Neurotransmitter Secretion
Pathways		RAB geranylgeranylation
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494)	Alcohol consumption (max-drinks) ( 29460428) Apolipoprotein B levels ( 32203549) Body mass index ( 26426971) Chloride levels ( 29403010) Coronary artery disease ( 32469254) LDL cholesterol levels ( 32203549) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Low density lipoprotein cholesterol levels ( 32154731 29403010) Low HDL-cholesterol levels ( 31006500) Platelet count ( 22139419) Serum uric acid levels ( 32514006) Urate levels ( 31578528)
Interacting Genes		16 interacting genes: ACVR1 CALM1 CALM2 CALM3 CHM GDI1 PIGR RABIF RIMS2 RPH3A RPH3AL SGSM2 SMAD1 SMAD4 TGFBR1 VRTN	12 interacting genes: ADD2 CASK GCH1 MYO5A NRXN1 RAB15 RAB27A RAB27B RAB3A RAB3B RAB8A YWHAH
Entrez ID		5865	22895
HPRD ID		01540	15273
Ensembl ID		ENSG00000169213	ENSG00000089169
Uniprot IDs		P20337	A0A024RBK6 Q9Y2J0
PDB IDs		3DZ8
Enriched GO Terms of Interacting Partners?
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