RAB3B and RPH3AL

Data Source:
HPRD (in vivo, in vitro)

		RAB3B	RPH3AL
Description		RAB3B, member RAS oncogene family	rabphilin 3A like (without C2 domains)
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Golgi Apparatus Cytosol Plasma Membrane Synaptic Vesicle Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome Dopaminergic Synapse Anchored Component Of Synaptic Vesicle Membrane	Cytoplasm Transport Vesicle Membrane Secretory Granule Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding	Protein Binding Cytoskeletal Protein Binding LIM Domain Binding Metal Ion Binding
	Biological Process	Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Antigen Processing And Presentation Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Protein Localization To Plasma Membrane Regulation Of Vesicle Size Regulation Of Synaptic Vesicle Cycle	Intracellular Protein Transport Exocytosis Regulation Of Exocytosis Response To Drug Positive Regulation Of Protein Secretion
Pathways		RAB geranylgeranylation
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494)	AIDS progression ( 21502085) Dimensional psychopathology (Cognitive) ( 29496196) Idiopathic intracranial hypertension ( 29608535) Impaired insulin sensitivity in response to n-3 PUFA supplementation ( 31779001)
Interacting Genes		16 interacting genes: ACVR1 CALM1 CALM2 CALM3 CHM GDI1 PIGR RABIF RIMS2 RPH3A RPH3AL SGSM2 SMAD1 SMAD4 TGFBR1 VRTN	25 interacting genes: ANKRD11 ATPAF2 C1orf109 HNRNPK KHDRBS3 MID2 MYO15B PNMA3 PRKAB2 PSME3 RAB27A RAB27B RAB3A RAB3B RAB3C RAB3D RAB3GAP1 RAB8A RIMS2 RSPH14 SAAL1 SCNM1 TCEA3 UNC13B ZYX
Entrez ID		5865	9501
HPRD ID		01540	05345
Ensembl ID		ENSG00000169213	ENSG00000181031
Uniprot IDs		P20337	A8K7D5 Q9UNE2
PDB IDs		3DZ8
Enriched GO Terms of Interacting Partners?
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