STX8 and SGPL1

  • Data Source:
  • BioGRID (two hybrid)

STX8

SGPL1

Description syntaxin 8 sphingosine-1-phosphate lyase 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576)
  • Borderline personality disorder ( 28632202)
  • Brain morphology (MOSTest) ( 32665545)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • HDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)
  • Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Immature fraction of reticulocytes ( 32888494)
  • Metabolite levels ( 23823483)
  • Microalbuminuria ( 26631737)
  • Red cell distribution width ( 32888494)
  • Reticulocyte fraction of red cells ( 32888494)
Interacting Genes 83 interacting genes: ACVR1 AMIGO1 AQP2 ASGR2 BCL2L13 BIK BSND CALM1 CD300E CD79A CERS4 CLDN9 CLN8 COPA CPLX4 CREB3 CREB3L1 DHRS9 EBP ERGIC3 FAM174A FAM209A FFAR2 FKBP7 FNDC9 GJA8 GJB1 GORAB GPR151 GPR152 GPR42 GPX8 JAGN1 JSRP1 KCNMB1 LMNA MCEE MCL1 MFF MGST2 MGST3 MMGT1 MS4A3 MTERF3 NAPA NAPG NCR3LG1 NDUFAF1 NDUFAF2 NSF PEX12 PSCA RETREG3 RNASEK SAR1A SCN3B SGPL1 SLC10A6 SLC18A1 SLC22A2 SSMEM1 STAR STMN4 STX1A STX2 STX4 STX5 STX7 TGFBR1 TMED8 TMEM14B TMEM179B TMEM205 TMEM237 TMEM86B TMPPE TMPRSS2 TSPAN12 VAMP5 VPS11 VPS18 VTI1B WDR91 35 interacting genes: AQP3 AQP9 BCL2L2 BRICD5 CCL4L2 CLDN19 EFNA5 ERG28 FA2H FAM177A1 FXYD3 HMOX2 IFITM3 MARCHF5 MFSD6 MIP MMD2 PAQR5 PLP2 PLPP4 RNASE10 RTP2 SCAMP5 SLC30A3 SRPK2 STATH STING1 STX4 STX8 TMEM176A TMEM242 TMEM97 TRARG1 TSPAN4 UNC50
Entrez ID 9482 8879
HPRD ID 05012 07224
Ensembl ID ENSG00000170310 ENSG00000166224
Uniprot IDs Q9UNK0 O95470
PDB IDs 4Q6R
Enriched GO Terms of Interacting Partners?
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