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STX8 and CREB3
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
STX8
CREB3
Description
syntaxin 8
cAMP responsive element binding protein 3
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Lysosomal Membrane
Endosome
Early Endosome
Late Endosome
Endoplasmic Reticulum
Trans-Golgi Network
Cytosol
Integral Component Of Plasma Membrane
Endomembrane System
Integral Component Of Membrane
SNARE Complex
Late Endosome Membrane
Vesicle
Phagocytic Vesicle
Perinuclear Region Of Cytoplasm
Recycling Endosome
Golgi Membrane
Chromatin
Nucleus
Nucleoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytosol
Integral Component Of Membrane
Molecular Function
SNARE Binding
SNAP Receptor Activity
Protein Binding
Chloride Channel Inhibitor Activity
Syntaxin Binding
Ubiquitin Protein Ligase Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
CAMP Response Element Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Intracellular Protein Transport
Vesicle Fusion
Endosome To Lysosome Transport
Early Endosome To Late Endosome Transport
Vesicle Docking
Cellular Response To Interferon-gamma
Regulation Of Protein Localization To Plasma Membrane
Regulation Of Transcription By RNA Polymerase II
Chemotaxis
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response
Viral Process
Endoplasmic Reticulum Unfolded Protein Response
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Monocyte Chemotaxis
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
CREB3 factors activate genes
CREB3 factors activate genes
Drugs
Diseases
GWAS
Blood protein levels (
30072576
)
Borderline personality disorder (
28632202
)
Brain morphology (MOSTest) (
32665545
)
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
HDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes (
28736931
)
Obstructive sleep apnea trait (apnea hypopnea index) (
29077507
)
Brain morphology (MOSTest) (
32665545
)
Interacting Genes
83 interacting genes:
ACVR1
AMIGO1
AQP2
ASGR2
BCL2L13
BIK
BSND
CALM1
CD300E
CD79A
CERS4
CLDN9
CLN8
COPA
CPLX4
CREB3
CREB3L1
DHRS9
EBP
ERGIC3
FAM174A
FAM209A
FFAR2
FKBP7
FNDC9
GJA8
GJB1
GORAB
GPR151
GPR152
GPR42
GPX8
JAGN1
JSRP1
KCNMB1
LMNA
MCEE
MCL1
MFF
MGST2
MGST3
MMGT1
MS4A3
MTERF3
NAPA
NAPG
NCR3LG1
NDUFAF1
NDUFAF2
NSF
PEX12
PSCA
RETREG3
RNASEK
SAR1A
SCN3B
SGPL1
SLC10A6
SLC18A1
SLC22A2
SSMEM1
STAR
STMN4
STX1A
STX2
STX4
STX5
STX7
TGFBR1
TMED8
TMEM14B
TMEM179B
TMEM205
TMEM237
TMEM86B
TMPPE
TMPRSS2
TSPAN12
VAMP5
VPS11
VPS18
VTI1B
WDR91
205 interacting genes:
ABHD16A
ACKR2
ACSF2
ACSL5
ADTRP
AGER
AGPAT3
ALG3
ALG8
APH1A
APOA2
APOD
APPBP2
AQP1
AQP2
AQP4
AQP5
ATF3
ATF4
ATP6AP2
ATP6V0C
BCAP29
BCAT2
BCL2L1
BIK
BNIP2
BNIP3
BTN2A2
C2
C3orf52
CACFD1
CCR1
CD207
CD82
CDS2
CEBPG
CELA3A
CES1
CFHR5
CGRRF1
CHMP7
CLCN7
CLDN19
CLDND2
CLP1
CMTM5
CNPY3
CREB3L1
CREB3L3
CT45A5
CTSW
CYB561
CYB5B
CYBC1
CYBRD1
CYP4F2
DDIT3
DNAJC30
DOLK
DRAM1
EBP
EMC6
EMD
ERG28
FA2H
FAM3A
FAM3C
FDFT1
FDPS
FIS1
FMO1
FMO3
FXYD3
FXYD6
GJA1
GJB2
GYPA
HCFC1
HDAC3
HMOX1
HVCN1
ICAM4
IGFBP5
ITM2B
JUN
KCNK1
KLHL30-AS1
KRTCAP2
LAT
LHFPL5
LILRB5
LMBR1L
LMNA
LPCAT2
LTA
MAL2
MALL
MARCHF5
MFSD11
MFSD5
MGST2
MRPL57
MS4A1
MYADM
NAA10
NDUFB6
NEU1
NFE2L2
NFE2L3
NFIL3
NKG7
NRG4
ORMDL1
OS9
P4HA2
PLLP
PLN
PLP1
PLPP1
PLTP
PMP22
PNLIPRP1
PSENEN
PTCH1
PTDSS1
PTPN9
RAB23
RABAC1
RHEB
RIMS3
RPRM
RPS3A
RRAS2
RUSF1
SACM1L
SAR1B
SCAMP4
SCAMP5
SCLY
SCP2
SEC22B
SEC61G
SELENOK
SERINC1
SFT2D2
SFTPC
SFXN3
SHMT2
SLC19A3
SLC29A1
SLC29A2
SLC29A3
SLC2A3
SLC2A4
SLC30A2
SLC35C2
SLC38A1
SLC39A13
SLC41A2
SLC41A3
SLC49A3
SLC50A1
SLC7A9
SPOCK3
SQLE
ST6GAL2
STARD3
STX7
STX8
SYNGR1
SYNPR
TAP1
TECR
TIMM17B
TIMM23B
TM4SF4
TMEM100
TMEM115
TMEM140
TMEM14A
TMEM14B
TMEM14C
TMEM19
TMEM203
TMEM222
TMEM230
TMEM234
TMEM243
TMEM51
TMEM54
TRAM1
TRAM1L1
TSPAN2
TSPAN4
TSPAN7
TTLL5
UBE2J1
UNC50
USE1
VKORC1
VTI1B
YIPF2
ZDHHC11
ZDHHC21
ZDHHC9
Entrez ID
9482
10488
HPRD ID
05012
07339
Ensembl ID
ENSG00000170310
ENSG00000107175
Uniprot IDs
Q9UNK0
O43889
PDB IDs
Enriched GO Terms of Interacting Partners
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