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CREB3 and DDIT3
Data Source:
BioGRID
(fluorescent resonance energy transfer)
CREB3
DDIT3
Description
cAMP responsive element binding protein 3
DNA damage inducible transcript 3
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Chromatin
Nucleus
Nucleoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytosol
Integral Component Of Membrane
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytoplasm
Late Endosome
Cytosol
Protein-DNA Complex
CHOP-C/EBP Complex
CHOP-ATF4 Complex
CHOP-ATF3 Complex
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
CAMP Response Element Binding
Sequence-specific Double-stranded DNA Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
CAMP Response Element Binding Protein Binding
Protein Homodimerization Activity
Leucine Zipper Domain Binding
Protein Heterodimerization Activity
Transcription Regulator Inhibitor Activity
Biological Process
Regulation Of Transcription By RNA Polymerase II
Chemotaxis
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response
Viral Process
Endoplasmic Reticulum Unfolded Protein Response
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Monocyte Chemotaxis
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Transcription By RNA Polymerase II
Blood Vessel Maturation
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Cellular Response To DNA Damage Stimulus
ER Overload Response
Response To Unfolded Protein
Cell Cycle Arrest
Sensory Perception Of Sound
Anterior/posterior Axis Specification
Regulation Of Autophagy
Wnt Signaling Pathway
Endoplasmic Reticulum Unfolded Protein Response
Negative Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Interferon-gamma Production
Negative Regulation Of Interleukin-17 Production
Negative Regulation Of Interleukin-4 Production
Positive Regulation Of Interleukin-8 Production
Negative Regulation Of CREB Transcription Factor Activity
Response To Endoplasmic Reticulum Stress
PERK-mediated Unfolded Protein Response
ATF6-mediated Unfolded Protein Response
Response To Starvation
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Neuron Apoptotic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Cell Redox Homeostasis
Negative Regulation Of Fat Cell Differentiation
Negative Regulation Of Myoblast Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of DNA-binding Transcription Factor Activity
Release Of Sequestered Calcium Ion Into Cytosol
Negative Regulation Of Protein Kinase B Signaling
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Establishment Of Protein Localization To Mitochondrion
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Cold-induced Thermogenesis
Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Intrinsic Apoptotic Signaling Pathway In Response To Nitrosative Stress
Negative Regulation Of Determination Of Dorsal Identity
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
CREB3 factors activate genes
CREB3 factors activate genes
ATF4 activates genes in response to endoplasmic reticulum stress
ATF6 (ATF6-alpha) activates chaperone genes
FOXO-mediated transcription of cell death genes
FOXO-mediated transcription of cell death genes
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK1 (HRI) to heme deficiency
Drugs
Diseases
Myxoid liposarcoma
GWAS
Brain morphology (MOSTest) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Interacting Genes
205 interacting genes:
ABHD16A
ACKR2
ACSF2
ACSL5
ADTRP
AGER
AGPAT3
ALG3
ALG8
APH1A
APOA2
APOD
APPBP2
AQP1
AQP2
AQP4
AQP5
ATF3
ATF4
ATP6AP2
ATP6V0C
BCAP29
BCAT2
BCL2L1
BIK
BNIP2
BNIP3
BTN2A2
C2
C3orf52
CACFD1
CCR1
CD207
CD82
CDS2
CEBPG
CELA3A
CES1
CFHR5
CGRRF1
CHMP7
CLCN7
CLDN19
CLDND2
CLP1
CMTM5
CNPY3
CREB3L1
CREB3L3
CT45A5
CTSW
CYB561
CYB5B
CYBC1
CYBRD1
CYP4F2
DDIT3
DNAJC30
DOLK
DRAM1
EBP
EMC6
EMD
ERG28
FA2H
FAM3A
FAM3C
FDFT1
FDPS
FIS1
FMO1
FMO3
FXYD3
FXYD6
GJA1
GJB2
GYPA
HCFC1
HDAC3
HMOX1
HVCN1
ICAM4
IGFBP5
ITM2B
JUN
KCNK1
KLHL30-AS1
KRTCAP2
LAT
LHFPL5
LILRB5
LMBR1L
LMNA
LPCAT2
LTA
MAL2
MALL
MARCHF5
MFSD11
MFSD5
MGST2
MRPL57
MS4A1
MYADM
NAA10
NDUFB6
NEU1
NFE2L2
NFE2L3
NFIL3
NKG7
NRG4
ORMDL1
OS9
P4HA2
PLLP
PLN
PLP1
PLPP1
PLTP
PMP22
PNLIPRP1
PSENEN
PTCH1
PTDSS1
PTPN9
RAB23
RABAC1
RHEB
RIMS3
RPRM
RPS3A
RRAS2
RUSF1
SACM1L
SAR1B
SCAMP4
SCAMP5
SCLY
SCP2
SEC22B
SEC61G
SELENOK
SERINC1
SFT2D2
SFTPC
SFXN3
SHMT2
SLC19A3
SLC29A1
SLC29A2
SLC29A3
SLC2A3
SLC2A4
SLC30A2
SLC35C2
SLC38A1
SLC39A13
SLC41A2
SLC41A3
SLC49A3
SLC50A1
SLC7A9
SPOCK3
SQLE
ST6GAL2
STARD3
STX7
STX8
SYNGR1
SYNPR
TAP1
TECR
TIMM17B
TIMM23B
TM4SF4
TMEM100
TMEM115
TMEM140
TMEM14A
TMEM14B
TMEM14C
TMEM19
TMEM203
TMEM222
TMEM230
TMEM234
TMEM243
TMEM51
TMEM54
TRAM1
TRAM1L1
TSPAN2
TSPAN4
TSPAN7
TTLL5
UBE2J1
UNC50
USE1
VKORC1
VTI1B
YIPF2
ZDHHC11
ZDHHC21
ZDHHC9
68 interacting genes:
AMOTL2
ATF2
ATF3
ATF4
ATPAF2
BACH1
BACH2
BATF
BATF2
BATF3
CCDC153
CDK6
CEBPA
CEBPB
CEBPE
CEBPG
CRACR2A
CREB3
CREB3L1
CREBL2
CSNK2A1
DBP
DGCR2
DNMT3L
EMSY
EP300
EPAS1
F2
FOS
FOSL1
FOSL2
GIMAP6
GIPC1
GP1BA
HOXA5
HSD17B14
IKBKG
JDP2
JUN
JUNB
JUND
KPNA2
LMO2
LNX1
MAFF
MAFG
MAPK14
MCMBP
NFIL3
PCM1
PICALM
POLR1D
RAI1
RPS3
RPS3A
SNAPC5
SPOP
SRA1
SSX3
TEDC1
TNFSF12
TRIB3
TXN2
TXNDC2
VPS37C
ZBTB25
ZC3H14
ZSCAN31
Entrez ID
10488
1649
HPRD ID
07339
00529
Ensembl ID
ENSG00000107175
ENSG00000175197
Uniprot IDs
O43889
P35638
Q53YD1
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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