ARHGAP29 and RAP2A

Data Source:
HPRD (two hybrid, in vitro)

		ARHGAP29	RAP2A
Description		Rho GTPase activating protein 29	RAP2A, member of RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Protein-containing Complex	Cytosol Plasma Membrane Midbody Recycling Endosome Recycling Endosome Membrane
	Molecular Function	GTPase Activator Activity PDZ Domain Binding Metal Ion Binding	Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Rho Protein Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Activation Of GTPase Activity	Positive Regulation Of Protein Phosphorylation Microvillus Assembly Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Positive Regulation Of Protein Autophosphorylation Rap Protein Signal Transduction Cellular Protein Localization Cellular Response To Drug Establishment Of Protein Localization Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of JNK Cascade Regulation Of Dendrite Morphogenesis Protein Localization To Plasma Membrane
Pathways		Rho GTPase cycle
Drugs			Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate
Diseases
GWAS		Cleft lip with or without cleft palate ( 28054174) D-dimer levels ( 21502573) Orofacial clefts ( 28054174) Plateletcrit ( 32888494) Systolic blood pressure ( 30224653)	Gut microbiota (bacterial taxa) ( 27723756) Peripheral artery disease ( 26488411)
Interacting Genes		7 interacting genes: HRAS KDM1A MAGEA11 PTPN13 RAP2A RHOA TRIM54	32 interacting genes: ACVR1 AFDN ARHGAP29 BMPR1B EEF1A1 ENSA FKBP2 FNTB FTL GABARAPL2 GRIN1 GRIN2D MAP4K4 NEDD4 PLG RAF1 RALGDS RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASIP1 RASSF5 RGL1 RGS14 RRP9 RUNDC3A SERPINA1 SMAD1 TGFBR1 TM7SF2 TNIK
Entrez ID		9411	5911
HPRD ID		06674	01547
Ensembl ID		ENSG00000137962	ENSG00000125249
Uniprot IDs		Q52LW3	P10114
PDB IDs			1KAO 2RAP 3RAP
Enriched GO Terms of Interacting Partners?
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