Description |
RAP2A, member of RAS oncogene family |
farnesyltransferase, CAAX box, beta |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- AZD3409
- Tipifarnib
- Lonafarnib
- 2-CHLORO-5-(3-CHLORO-PHENYL)-6-[(4-CYANO-PHENYL)-(3-METHYL-3H-IMIDAZOL-4-YL)- METHOXYMETHYL]-NICOTINONITRILE
- (11S)-8-CHLORO-11-[1-(METHYLSULFONYL)PIPERIDIN-4-YL]-6-PIPERAZIN-1-YL-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDINE
- L-778123
- [(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID
- Farnesyl diphosphate
- Geranylgeranyl diphosphate
- ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID
- (20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1,6,9,12]OXATRIAZA-CYCLOOCTADECOSINE-9-CARBONITRILE
- (20S)-19,20,22,23-TETRAHYDRO-19-OXO-5H,21H-18,20-ETHANO-12,14-ETHENO-6,10-METHENOBENZ[D]IMIDAZO[4,3-L][1,6,9,13]OXATRIAZACYCLONOADECOSINE-9-CARBONITRILE
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Diseases |
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GWAS |
- Gut microbiota (bacterial taxa) ( 27723756)
- Peripheral artery disease ( 26488411)
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Interacting Genes |
32 interacting genes:
ACVR1
AFDN
ARHGAP29
BMPR1B
EEF1A1
ENSA
FKBP2
FNTB
FTL
GABARAPL2
GRIN1
GRIN2D
MAP4K4
NEDD4
PLG
RAF1
RALGDS
RAPGEF3
RAPGEF4
RAPGEF5
RAPGEF6
RASIP1
RASSF5
RGL1
RGS14
RRP9
RUNDC3A
SERPINA1
SMAD1
TGFBR1
TM7SF2
TNIK
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17 interacting genes:
AGXT
APOL6
ATPAF2
CCDC24
CENPF
FNTA
GBP1
HDAC6
HOXC8
HRAS
KRAS
KRBA1
PTP4A3
RAP2A
RRAS2
SMG9
TLX3
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Entrez ID |
5911 |
2342 |
HPRD ID |
01547 |
00608 |
Ensembl ID |
ENSG00000125249
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ENSG00000257365
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Uniprot IDs |
P10114
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A0A384MEJ5
P49356
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PDB IDs |
1KAO
2RAP
3RAP
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1JCQ
1LD7
1LD8
1MZC
1S63
1SA4
1TN6
2F0Y
2H6F
2H6G
2H6H
2H6I
2IEJ
3E37
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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