RAP2A and ARHGAP29

Data Source:
HPRD (two hybrid, in vitro)

		RAP2A	ARHGAP29
Description		RAP2A, member of RAS oncogene family	Rho GTPase activating protein 29
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Midbody Recycling Endosome Recycling Endosome Membrane	Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding GDP Binding	GTPase Activator Activity PDZ Domain Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Microvillus Assembly Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Positive Regulation Of Protein Autophosphorylation Rap Protein Signal Transduction Cellular Protein Localization Cellular Response To Drug Establishment Of Protein Localization Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of JNK Cascade Regulation Of Dendrite Morphogenesis Protein Localization To Plasma Membrane	Rho Protein Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Activation Of GTPase Activity
Pathways			Rho GTPase cycle
Drugs		Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate
Diseases
GWAS		Gut microbiota (bacterial taxa) ( 27723756) Peripheral artery disease ( 26488411)	Cleft lip with or without cleft palate ( 28054174) D-dimer levels ( 21502573) Orofacial clefts ( 28054174) Plateletcrit ( 32888494) Systolic blood pressure ( 30224653)
Interacting Genes		32 interacting genes: ACVR1 AFDN ARHGAP29 BMPR1B EEF1A1 ENSA FKBP2 FNTB FTL GABARAPL2 GRIN1 GRIN2D MAP4K4 NEDD4 PLG RAF1 RALGDS RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASIP1 RASSF5 RGL1 RGS14 RRP9 RUNDC3A SERPINA1 SMAD1 TGFBR1 TM7SF2 TNIK	7 interacting genes: HRAS KDM1A MAGEA11 PTPN13 RAP2A RHOA TRIM54
Entrez ID		5911	9411
HPRD ID		01547	06674
Ensembl ID		ENSG00000125249	ENSG00000137962
Uniprot IDs		P10114	Q52LW3
PDB IDs		1KAO 2RAP 3RAP
Enriched GO Terms of Interacting Partners?
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