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ORMDL1 and MFSD14B
Data Source:
BioGRID
(two hybrid)
ORMDL1
MFSD14B
Description
ORMDL sphingolipid biosynthesis regulator 1
major facilitator superfamily domain containing 14B
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
SPOTS Complex
Integral Component Of Membrane
Molecular Function
Protein Binding
Protein Binding
Transmembrane Transporter Activity
Biological Process
Ceramide Metabolic Process
Cellular Sphingolipid Homeostasis
Negative Regulation Of Ceramide Biosynthetic Process
Transmembrane Transport
Pathways
Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS
Bilirubin levels (
20639394
)
Ferritin levels (
25162662
)
Interacting Genes
37 interacting genes:
APP
AQP6
ARL13B
ASGR2
COQ9
CPLX4
CREB3
CREB3L1
EBAG9
EBP
EHHADH
ERGIC3
GPR152
HSD17B11
KCNK4
LMNA
LNX1
MFSD14B
PCNX2
PGRMC2
REEP4
SAR1A
SCN3B
SLC10A1
SLC10A6
SLC18A1
SLC30A8
SLC35C2
STOM
TLCD4
TMEM143
TMEM14B
TMEM35A
TMEM52B
VMA21
ZDHHC15
ZFYVE27
75 interacting genes:
ADIPOQ
AGPAT3
AGPAT4
ARL6IP1
ATP13A1
BNIP3
C14orf180
C4orf3
CCL4L2
CFHR5
CLDN4
CMTM3
COMT
CSGALNACT2
CTSA
CYB5B
CYBC1
DEFB127
DNAJC30
EMC6
ERG28
FKBP8
FMO1
FUNDC2
GIMAP1
GOSR2
GRM2
KTN1
LAT
LEPROTL1
LPCAT2
LRP10
MGLL
MS4A1
NAT8
ORMDL1
PEX16
PKMYT1
PRRT2
RNF24
SACM1L
SCD
SERP1
SERP2
SLC25A46
SLC39A9
SLC66A2
SMAGP
STX3
TECR
THSD7B
TIMMDC1
TMBIM6
TMEM119
TMEM167B
TMEM176A
TMEM19
TMEM208
TMEM229B
TMEM239
TMEM31
TMX2
TPRG1
TRARG1
TREX1
TSNARE1
UBE2J1
UNC50
USE1
YIPF1
YIPF2
YIPF4
YIPF6
ZDHHC24
ZFPL1
Entrez ID
94101
84641
HPRD ID
15092
07869
Ensembl ID
ENSG00000128699
ENSG00000148110
Uniprot IDs
Q9P0S3
Q5SR56
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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