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ORMDL1 and SLC35C2
Data Source:
BioGRID
(two hybrid)
ORMDL1
SLC35C2
Description
ORMDL sphingolipid biosynthesis regulator 1
solute carrier family 35 member C2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
SPOTS Complex
Nucleoplasm
Endoplasmic Reticulum-Golgi Intermediate Compartment
Golgi Apparatus
Cis-Golgi Network
Integral Component Of Membrane
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Molecular Function
Protein Binding
Antiporter Activity
Biological Process
Ceramide Metabolic Process
Cellular Sphingolipid Homeostasis
Negative Regulation Of Ceramide Biosynthetic Process
Negative Regulation Of Gene Expression
UDP-glucose Transmembrane Transport
Protein O-linked Fucosylation
Positive Regulation Of Notch Signaling Pathway
Pathways
Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS
Bilirubin levels (
20639394
)
Ferritin levels (
25162662
)
Interacting Genes
37 interacting genes:
APP
AQP6
ARL13B
ASGR2
COQ9
CPLX4
CREB3
CREB3L1
EBAG9
EBP
EHHADH
ERGIC3
GPR152
HSD17B11
KCNK4
LMNA
LNX1
MFSD14B
PCNX2
PGRMC2
REEP4
SAR1A
SCN3B
SLC10A1
SLC10A6
SLC18A1
SLC30A8
SLC35C2
STOM
TLCD4
TMEM143
TMEM14B
TMEM35A
TMEM52B
VMA21
ZDHHC15
ZFYVE27
91 interacting genes:
ACSL5
ADIPOQ
AGPAT3
AGPAT4
APOD
ARL6IP1
ASGR1
ATP13A1
BCL2L2
BMP10
C14orf180
C2
C4orf3
CCDC167
CLDN19
CMTM5
CNIH1
COL4A5
CREB3
CREB3L1
CYB561
CYBC1
DNAJC30
EFNA5
EMP3
FAM3C
FDFT1
FFAR2
FXYD3
FXYD6
FXYD6-FXYD2
GIMAP5
GOLT1A
GPR152
ITGAM
LAT
LEPROTL1
LHFPL5
LPAR3
MAL
MAL2
MALL
MS4A1
NRM
ORMDL1
ORMDL3
PDCD1LG2
PEX16
PLN
PLP2
PNLIPRP1
PRB1
RUSF1
SACM1L
SEC22A
SEC22B
SELENOK
SERP1
SLC10A6
SLC12A7
SLC30A3
SLC35F1
SLC66A1
SMCO4
SSMEM1
STRIT1
STX3
SYNDIG1
SYS1
TAP1
THBD
TMEM107
TMEM14B
TMEM239
TMEM31
TMEM50B
TMEM65
TMEM86A
TPRG1
TSNARE1
TSPAN2
TSPAN33
TVP23B
UNC93B1
UPK1B
VAPB
VEGFA
VTI1B
YIF1A
YIPF4
YIPF6
Entrez ID
94101
51006
HPRD ID
15092
15371
Ensembl ID
ENSG00000128699
ENSG00000080189
Uniprot IDs
Q9P0S3
B7Z6R4
Q9NQQ7
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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