MFSD14B and MS4A1

Data Source:
BioGRID (two hybrid)

		MFSD14B	MS4A1
Description		major facilitator superfamily domain containing 14B	membrane spanning 4-domains A1
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Extracellular Space Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Plasma Membrane Raft Extracellular Exosome
	Molecular Function	Protein Binding Transmembrane Transporter Activity	Epidermal Growth Factor Receptor Binding Protein Binding Immunoglobulin Binding MHC Class II Protein Complex Binding Identical Protein Binding
	Biological Process	Transmembrane Transport	Store-operated Calcium Entry Humoral Immune Response Response To Bacterium B Cell Differentiation B Cell Proliferation B Cell Activation B Cell Receptor Signaling Pathway Protein Tetramerization Calcium Ion Import Into Cytosol
Pathways
Drugs			Rituximab Ibritumomab tiuxetan Tositumomab Ofatumumab Obinutuzumab Technetium Tc-99m nofetumomab merpentan Ocrelizumab
Diseases
GWAS			Recurrent major depressive disorder ( 29317602)
Interacting Genes		75 interacting genes: ADIPOQ AGPAT3 AGPAT4 ARL6IP1 ATP13A1 BNIP3 C14orf180 C4orf3 CCL4L2 CFHR5 CLDN4 CMTM3 COMT CSGALNACT2 CTSA CYB5B CYBC1 DEFB127 DNAJC30 EMC6 ERG28 FKBP8 FMO1 FUNDC2 GIMAP1 GOSR2 GRM2 KTN1 LAT LEPROTL1 LPCAT2 LRP10 MGLL MS4A1 NAT8 ORMDL1 PEX16 PKMYT1 PRRT2 RNF24 SACM1L SCD SERP1 SERP2 SLC25A46 SLC39A9 SLC66A2 SMAGP STX3 TECR THSD7B TIMMDC1 TMBIM6 TMEM119 TMEM167B TMEM176A TMEM19 TMEM208 TMEM229B TMEM239 TMEM31 TMX2 TPRG1 TRARG1 TREX1 TSNARE1 UBE2J1 UNC50 USE1 YIPF1 YIPF2 YIPF4 YIPF6 ZDHHC24 ZFPL1	41 interacting genes: ACKR2 AQP6 CD40 CERS4 CLEC14A CREB3 CREB3L1 CSNK2A1 CSNK2A2 FAM209A FCRL3 FYN GORAB GPR42 HSD17B11 HSD17B13 IL7R KASH5 LCK LEUTX LMNA LYN MDM2 MFSD14B MMD MTIF3 REEP2 REEP4 RNF19B RNF5 SLC10A1 SLC10A6 SLC18A1 SLC35C2 THAP4 TMEM31 TMEM72 TMEM82 TMPPE TMX2 TSPO2
Entrez ID		84641	931
HPRD ID		07869	00204
Ensembl ID		ENSG00000148110	ENSG00000156738
Uniprot IDs		Q5SR56	A0A024R507 P11836
PDB IDs			1S8B 2OSL 3BKY 3PP4 6VJA 6Y90 6Y92 6Y97 6Y9A
Enriched GO Terms of Interacting Partners?
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