ORMDL1 and SLC10A6

Data Source:
BioGRID (two hybrid)

		ORMDL1	SLC10A6
Description		ORMDL sphingolipid biosynthesis regulator 1	solute carrier family 10 member 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane SPOTS Complex	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding Bile Acid:sodium Symporter Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity
	Biological Process	Ceramide Metabolic Process Cellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process	Sodium Ion Transport Bile Acid And Bile Salt Transport Sodium-dependent Organic Anion Transport Transmembrane Transport
Pathways		Sphingolipid de novo biosynthesis	Transport of bile salts and organic acids, metal ions and amine compounds
Drugs
Diseases
GWAS		Bilirubin levels ( 20639394) Ferritin levels ( 25162662)	Eyebrow thickness ( 26926045) Insulin-related traits ( 22791750) Refractive error ( 32231278)
Interacting Genes		37 interacting genes: APP AQP6 ARL13B ASGR2 COQ9 CPLX4 CREB3 CREB3L1 EBAG9 EBP EHHADH ERGIC3 GPR152 HSD17B11 KCNK4 LMNA LNX1 MFSD14B PCNX2 PGRMC2 REEP4 SAR1A SCN3B SLC10A1 SLC10A6 SLC18A1 SLC30A8 SLC35C2 STOM TLCD4 TMEM143 TMEM14B TMEM35A TMEM52B VMA21 ZDHHC15 ZFYVE27	146 interacting genes: ACSL5 ANKRD46 APOD ARL6IP1 ARV1 ATP13A1 BMP10 BTN2A2 C11orf24 C2CD2L CCDC167 CCL4 CDIPT CDS1 CLDND2 CMTM5 CNIH1 COL4A5 COMT COX20 CYB5B CYB5R3 CYP4F2 DERL1 DGAT2L6 EMC6 ERG28 FA2H FAM3C FAXDC2 FIS1 FKBP8 FMO1 FUNDC2 FXYD3 FXYD6 FXYD6-FXYD2 GIMAP1 GJB6 GLB1 GOLT1B GOSR2 GPR151 GYPA GYPC HTATIP2 IGFBP5 ITGAM LPAR3 LSS MALL MFSD5 MFSD6 MGLL MS4A1 NAT8 NEU1 NINJ2 NRM OR7D4 ORMDL1 OSMR PEDS1-UBE2V1 PEX16 PIP4P1 PIP4P2 PLLP PLP1 PNLIPRP1 PRAF2 PRRT2 PSEN1 PSENEN RNF24 RTP2 RUSF1 SACM1L SCAMP4 SCAMP5 SCD SERP1 SERP2 SFT2D2 SFXN1 SLC12A7 SLC25A46 SLC29A2 SLC30A2 SLC30A3 SLC35C2 SLC35G2 SLC38A1 SLC39A6 SLC39A9 SLC41A1 SLC66A2 SLC7A1 SMAGP SMIM1 SNORC STATH STX12 STX7 STX8 SYNGR1 SYNJ2BP TAP1 TECR TF TM4SF4 TMEM107 TMEM11 TMEM119 TMEM120B TMEM128 TMEM143 TMEM14A TMEM14C TMEM203 TMEM208 TMEM218 TMEM229B TMEM234 TMEM239 TMEM242 TMEM252 TMEM262 TMEM50B TMEM60 TMEM65 TMEM86A TMEM86B TPRG1 TREX1 TSNARE1 TSPAN2 TSPO2 TVP23B UBE2J1 UNC50 VAMP4 YIPF1 YIPF2 YIPF6 ZDHHC15 ZFPL1
Entrez ID		94101	345274
HPRD ID		15092	11593
Ensembl ID		ENSG00000128699	ENSG00000145283
Uniprot IDs		Q9P0S3	Q3KNW5
PDB IDs
Enriched GO Terms of Interacting Partners?
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