SLC35C2 and ACSL5

Data Source:
BioGRID (two hybrid)

		SLC35C2	ACSL5
Description		solute carrier family 35 member C2	acyl-CoA synthetase long chain family member 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Nucleoplasm Nucleolus Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Antiporter Activity	Long-chain Fatty Acid-CoA Ligase Activity Protein Binding ATP Binding Arachidonate-CoA Ligase Activity
	Biological Process	Negative Regulation Of Gene Expression UDP-glucose Transmembrane Transport Protein O-linked Fucosylation Positive Regulation Of Notch Signaling Pathway	Long-chain Fatty Acid Metabolic Process Lipid Biosynthetic Process Positive Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Long-chain Fatty-acyl-CoA Biosynthetic Process
Pathways			Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS			Amyotrophic lateral sclerosis ( 32968195) Basophil percentage of white cells ( 32888494) High chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494)
Interacting Genes		91 interacting genes: ACSL5 ADIPOQ AGPAT3 AGPAT4 APOD ARL6IP1 ASGR1 ATP13A1 BCL2L2 BMP10 C14orf180 C2 C4orf3 CCDC167 CLDN19 CMTM5 CNIH1 COL4A5 CREB3 CREB3L1 CYB561 CYBC1 DNAJC30 EFNA5 EMP3 FAM3C FDFT1 FFAR2 FXYD3 FXYD6 FXYD6-FXYD2 GIMAP5 GOLT1A GPR152 ITGAM LAT LEPROTL1 LHFPL5 LPAR3 MAL MAL2 MALL MS4A1 NRM ORMDL1 ORMDL3 PDCD1LG2 PEX16 PLN PLP2 PNLIPRP1 PRB1 RUSF1 SACM1L SEC22A SEC22B SELENOK SERP1 SLC10A6 SLC12A7 SLC30A3 SLC35F1 SLC66A1 SMCO4 SSMEM1 STRIT1 STX3 SYNDIG1 SYS1 TAP1 THBD TMEM107 TMEM14B TMEM239 TMEM31 TMEM50B TMEM65 TMEM86A TPRG1 TSNARE1 TSPAN2 TSPAN33 TVP23B UNC93B1 UPK1B VAPB VEGFA VTI1B YIF1A YIPF4 YIPF6	13 interacting genes: AQP6 CREB3 EBAG9 FBXO7 PEX12 RETREG3 SELENOI SLC10A1 SLC10A6 SLC16A7 SLC35C2 SLC7A14 TMEM14B
Entrez ID		51006	51703
HPRD ID		15371	16139
Ensembl ID		ENSG00000080189	ENSG00000197142
Uniprot IDs		B7Z6R4 Q9NQQ7	Q9ULC5
PDB IDs
Enriched GO Terms of Interacting Partners?
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