SLC10A6 and GLB1

Data Source:
BioGRID (two hybrid)

		SLC10A6	GLB1
Description		solute carrier family 10 member 6	galactosidase beta 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Extracellular Region Cytoplasm Vacuole Golgi Apparatus Azurophil Granule Lumen Lysosomal Lumen Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Bile Acid:sodium Symporter Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity	Beta-galactosidase Activity Protein Binding Galactoside Binding Protein Homodimerization Activity
	Biological Process	Sodium Ion Transport Bile Acid And Bile Salt Transport Sodium-dependent Organic Anion Transport Transmembrane Transport	Glycosaminoglycan Catabolic Process Glycosphingolipid Metabolic Process Galactose Catabolic Process Keratan Sulfate Catabolic Process Neutrophil Degranulation Cellular Carbohydrate Metabolic Process Response To Cortisone Response To Thyroglobulin Triiodothyronine
Pathways		Transport of bile salts and organic acids, metal ions and amine compounds	Glycosphingolipid metabolism Keratan sulfate degradation HS-GAG degradation MPS IV - Morquio syndrome B Sialic acid metabolism Defective NEU1 causes sialidosis Neutrophil degranulation
Drugs			Lactose
Diseases			Galactosialidosis GM1 gangliosidosis Mucopolysaccharidosis type IV (MPS4), including: Morquio syndrome A (MPS4A); Morquio syndrome B (MPS4B)
GWAS		Eyebrow thickness ( 26926045) Insulin-related traits ( 22791750) Refractive error ( 32231278)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 31361310 31959851 30929738 32296059 31619474) Asthma (adult onset) ( 30929738) Asthma (childhood onset) ( 31036433 30929738) Atopic dermatitis ( 23042114) Celiac disease ( 22057235) Eosinophil counts ( 29403010 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hepatocellular carcinoma ( 21105107) Medication use (adrenergics, inhalants) ( 31015401) Medication use (glucocorticoids) ( 31015401) Neutrophil percentage of granulocytes ( 27863252) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		146 interacting genes: ACSL5 ANKRD46 APOD ARL6IP1 ARV1 ATP13A1 BMP10 BTN2A2 C11orf24 C2CD2L CCDC167 CCL4 CDIPT CDS1 CLDND2 CMTM5 CNIH1 COL4A5 COMT COX20 CYB5B CYB5R3 CYP4F2 DERL1 DGAT2L6 EMC6 ERG28 FA2H FAM3C FAXDC2 FIS1 FKBP8 FMO1 FUNDC2 FXYD3 FXYD6 FXYD6-FXYD2 GIMAP1 GJB6 GLB1 GOLT1B GOSR2 GPR151 GYPA GYPC HTATIP2 IGFBP5 ITGAM LPAR3 LSS MALL MFSD5 MFSD6 MGLL MS4A1 NAT8 NEU1 NINJ2 NRM OR7D4 ORMDL1 OSMR PEDS1-UBE2V1 PEX16 PIP4P1 PIP4P2 PLLP PLP1 PNLIPRP1 PRAF2 PRRT2 PSEN1 PSENEN RNF24 RTP2 RUSF1 SACM1L SCAMP4 SCAMP5 SCD SERP1 SERP2 SFT2D2 SFXN1 SLC12A7 SLC25A46 SLC29A2 SLC30A2 SLC30A3 SLC35C2 SLC35G2 SLC38A1 SLC39A6 SLC39A9 SLC41A1 SLC66A2 SLC7A1 SMAGP SMIM1 SNORC STATH STX12 STX7 STX8 SYNGR1 SYNJ2BP TAP1 TECR TF TM4SF4 TMEM107 TMEM11 TMEM119 TMEM120B TMEM128 TMEM143 TMEM14A TMEM14C TMEM203 TMEM208 TMEM218 TMEM229B TMEM234 TMEM239 TMEM242 TMEM252 TMEM262 TMEM50B TMEM60 TMEM65 TMEM86A TMEM86B TPRG1 TREX1 TSNARE1 TSPAN2 TSPO2 TVP23B UBE2J1 UNC50 VAMP4 YIPF1 YIPF2 YIPF6 ZDHHC15 ZFPL1	11 interacting genes: CSNK2B CTSA DNAJB1 FOS GOLM1 NEU1 PLK1 SLC10A6 SLC30A2 SLC7A1 TK1
Entrez ID		345274	2720
HPRD ID		11593	01975
Ensembl ID		ENSG00000145283	ENSG00000170266
Uniprot IDs		Q3KNW5	B7Z6Q5 P16278
PDB IDs			3THC 3THD 3WEZ 3WF0 3WF1 3WF2 3WF3 3WF4
Enriched GO Terms of Interacting Partners?
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