ARHGAP18 and PALS2

Data Source:
HPRD (two hybrid)

		ARHGAP18	PALS2
Description		Rho GTPase activating protein 18	protein associated with LIN7 2, MAGUK family member
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ruffle Cytoplasm Cytosol Cytoplasmic Microtubule Plasma Membrane Nuclear Speck	Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	GTPase Activator Activity Cadherin Binding	Protein Binding
	Biological Process	Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Regulation Of Actin Filament Polymerization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Cell Motility	Protein-containing Complex Assembly
Pathways		Rho GTPase cycle
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel) ( 23648065) Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Axial length ( 24144296) Cognitive function ( 24684796) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Periodontal disease-related phenotype (Socransky) ( 24347629)
Interacting Genes		2 interacting genes: MPHOSPH6 PALS2	30 interacting genes: AATF ABCA1 ARHGAP18 DIS3 DNM2 DYNLRB1 EIF3G EXOSC10 EXOSC2 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FTL KHDRBS1 KNSTRN LIN7A LIN7B LIN7C MT2P1 MTREX NDN NFKB1 PARN RPS20 SMARCA4 SNX9 THOP1
Entrez ID		93663	51678
HPRD ID		12474	09509
Ensembl ID		ENSG00000146376	ENSG00000105926
Uniprot IDs		Q8N392	A0A024RA25 B8ZZG1 Q9NZW5
PDB IDs
Enriched GO Terms of Interacting Partners?
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