ADGRG1 and CCR9

Data Source:
BioGRID (two hybrid)

		ADGRG1	CCR9
Description		adhesion G protein-coupled receptor G1	C-C motif chemokine receptor 9
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Integral Component Of Membrane Membrane Raft Extracellular Exosome Glial Limiting End-foot	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Collagen Binding Heparin Binding Extracellular Matrix Binding	Chemokine Receptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding
	Biological Process	Angiogenesis Cell Adhesion Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Rho Protein Signal Transduction Cell-cell Signaling Brain Development Negative Regulation Of Cell Population Proliferation Vascular Endothelial Growth Factor Production Cell Migration Cerebral Cortex Regionalization Cerebral Cortex Radial Glia Guided Migration Layer Formation In Cerebral Cortex Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cell Adhesion Hematopoietic Stem Cell Homeostasis Protein Kinase C Signaling Seminiferous Tubule Development Positive Regulation Of Neural Precursor Cell Proliferation Negative Regulation Of Neuron Migration	CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Chemotaxis Immune Response Cellular Defense Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Viral Process Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway
Pathways			Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs			Vercirnon
Diseases		Polymicrogyria; Bilateral frontal polymicrogyria (BFP); Bilateral frontoparietal polymicrogyria (BFPP); Bilateral perisylvian polymicrogyria (BPP); Bilateral parasagittal parieto-occipital polymicrogyria (BPOP); Bilateral generalised polymicrogyria (BGP); Unilateral Polymicrogyria (ULP)
GWAS			Celiac disease ( 20190752) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)
Interacting Genes		3 interacting genes: ADRB2 CCR9 DRD2	19 interacting genes: ADGRG1 AIG1 CCL25 CD81 DGAT1 G6PC3 HLA-A KDELR1 NEU1 OSTC RHBDD2 SAP130 SCAMP4 SPNS1 TMC6 TRPM4 TSPAN7 TTYH1 YWHAE
Entrez ID		9289	10803
HPRD ID		06824	09200
Ensembl ID		ENSG00000205336	ENSG00000173585
Uniprot IDs		A0A024R6U7 A0A0S2Z517 B3KQN7 B3KQV4 B4DM06 Q9Y653	B2R734 P51686
PDB IDs			5LWE
Enriched GO Terms of Interacting Partners?
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