CCR9 and TMC6

Data Source:
BioGRID (two hybrid)

		CCR9	TMC6
Description		C-C motif chemokine receptor 9	transmembrane channel like 6
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Nuclear Membrane Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Chemokine Receptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding	Protein Binding Mechanosensitive Ion Channel Activity
	Biological Process	CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Chemotaxis Immune Response Cellular Defense Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Viral Process Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Biological_process Ion Transmembrane Transport Neutrophil Degranulation
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Neutrophil degranulation
Drugs		Vercirnon
Diseases			Epidermodysplasia verruciformis
GWAS		Celiac disease ( 20190752) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)	Glycated hemoglobin levels ( 31213470 28887542 29170429) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin A1c levels ( 29403010) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin ( 29403010 32888494 27863252) Mean corpuscular volume ( 29403010 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494 27863252) Red blood cell count ( 29403010 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Serum uric acid levels ( 29559957)
Interacting Genes		19 interacting genes: ADGRG1 AIG1 CCL25 CD81 DGAT1 G6PC3 HLA-A KDELR1 NEU1 OSTC RHBDD2 SAP130 SCAMP4 SPNS1 TMC6 TRPM4 TSPAN7 TTYH1 YWHAE	3 interacting genes: CCR9 ZBTB2 ZDHHC17
Entrez ID		10803	11322
HPRD ID		09200	08386
Ensembl ID		ENSG00000173585	ENSG00000141524
Uniprot IDs		B2R734 P51686	A0A024R8V2 Q7Z403
PDB IDs		5LWE
Enriched GO Terms of Interacting Partners?
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