CCR9 and ADGRG1

Data Source:
BioGRID (two hybrid)

		CCR9	ADGRG1
Description		C-C motif chemokine receptor 9	adhesion G protein-coupled receptor G1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface	Integral Component Of Plasma Membrane Integral Component Of Membrane Membrane Raft Extracellular Exosome Glial Limiting End-foot
	Molecular Function	Chemokine Receptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding	G Protein-coupled Receptor Activity Protein Binding Collagen Binding Heparin Binding Extracellular Matrix Binding
	Biological Process	CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Chemotaxis Immune Response Cellular Defense Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Viral Process Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Angiogenesis Cell Adhesion Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Rho Protein Signal Transduction Cell-cell Signaling Brain Development Negative Regulation Of Cell Population Proliferation Vascular Endothelial Growth Factor Production Cell Migration Cerebral Cortex Regionalization Cerebral Cortex Radial Glia Guided Migration Layer Formation In Cerebral Cortex Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cell Adhesion Hematopoietic Stem Cell Homeostasis Protein Kinase C Signaling Seminiferous Tubule Development Positive Regulation Of Neural Precursor Cell Proliferation Negative Regulation Of Neuron Migration
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs		Vercirnon
Diseases			Polymicrogyria; Bilateral frontal polymicrogyria (BFP); Bilateral frontoparietal polymicrogyria (BFPP); Bilateral perisylvian polymicrogyria (BPP); Bilateral parasagittal parieto-occipital polymicrogyria (BPOP); Bilateral generalised polymicrogyria (BGP); Unilateral Polymicrogyria (ULP)
GWAS		Celiac disease ( 20190752) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)
Interacting Genes		19 interacting genes: ADGRG1 AIG1 CCL25 CD81 DGAT1 G6PC3 HLA-A KDELR1 NEU1 OSTC RHBDD2 SAP130 SCAMP4 SPNS1 TMC6 TRPM4 TSPAN7 TTYH1 YWHAE	3 interacting genes: ADRB2 CCR9 DRD2
Entrez ID		10803	9289
HPRD ID		09200	06824
Ensembl ID		ENSG00000173585	ENSG00000205336
Uniprot IDs		B2R734 P51686	A0A024R6U7 A0A0S2Z517 B3KQN7 B3KQV4 B4DM06 Q9Y653
PDB IDs		5LWE
Enriched GO Terms of Interacting Partners?
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