CCR9 and KDELR1

Data Source:
BioGRID (two hybrid)

		CCR9	KDELR1
Description		C-C motif chemokine receptor 9	KDEL endoplasmic reticulum protein retention receptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Cis-Golgi Network Integral Component Of Membrane Transport Vesicle COPI-coated Vesicle Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Chemokine Receptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding	KDEL Sequence Binding Protein Binding ER Retention Sequence Binding
	Biological Process	CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Chemotaxis Immune Response Cellular Defense Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Viral Process Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Protein Retention In ER Lumen Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs		Vercirnon
Diseases
GWAS		Celiac disease ( 20190752) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)
Interacting Genes		19 interacting genes: ADGRG1 AIG1 CCL25 CD81 DGAT1 G6PC3 HLA-A KDELR1 NEU1 OSTC RHBDD2 SAP130 SCAMP4 SPNS1 TMC6 TRPM4 TSPAN7 TTYH1 YWHAE	12 interacting genes: ARF1 ARFGAP1 CCR9 COPB1 DLG2 DLG3 F2RL1 GPR35 KRT34 LIG4 PRKACA SEC23B
Entrez ID		10803	10945
HPRD ID		09200	00569
Ensembl ID		ENSG00000173585	ENSG00000105438
Uniprot IDs		B2R734 P51686	P24390
PDB IDs		5LWE
Enriched GO Terms of Interacting Partners?
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