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UBE2L6 and MID1
Data Source:
BioGRID
(two hybrid)
UBE2L6
MID1
Description
ubiquitin conjugating enzyme E2 L6
midline 1
Image
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Cytosol
Spindle
Cytosol
Microtubule
Microtubule Associated Complex
Cytoplasmic Microtubule
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Ubiquitin Protein Ligase Binding
ISG15 Transferase Activity
Ubiquitin Binding
Ubiquitin Conjugating Enzyme Activity
Protein Binding
Microtubule Binding
Zinc Ion Binding
Transferase Activity
Enzyme Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Protein Homodimerization Activity
Phosphoprotein Binding
Biological Process
Protein Polyubiquitination
Cellular Protein Modification Process
Ubiquitin-dependent Protein Catabolic Process
Protein Phosphopantetheinylation
Translesion Synthesis
ISG15-protein Conjugation
Negative Regulation Of Type I Interferon Production
Cellular Protein Metabolic Process
Microtubule Cytoskeleton Organization
Pattern Specification Process
Positive Regulation Of Stress-activated MAPK Cascade
Protein Localization To Microtubule
Interferon-gamma-mediated Signaling Pathway
Pathways
ISG15 antiviral mechanism
DDX58/IFIH1-mediated induction of interferon-alpha/beta
Termination of translesion DNA synthesis
Negative regulators of DDX58/IFIH1 signaling
Negative regulators of DDX58/IFIH1 signaling
Amyloid fiber formation
Antigen processing: Ubiquitination & Proteasome degradation
Interferon gamma signaling
Drugs
Diseases
Opitz-GBBB syndrome
GWAS
Blood protein levels (
28240269
)
Interacting Genes
40 interacting genes:
ARHGDIA
ARIH1
ARIH2
CBLC
DTX3
FLT3
HERC5
LONRF1
MAP3K1
MID1
MUL1
NEDD4L
PJA2
PRKN
RBCK1
RBX1
RNF122
RNF125
RNF144A
RNF144B
RNF150
RNF19A
RNF216
RNF25
RNF4
RNF40
RUNX1
SIAH1
SIAH2
SPEN
TOPORS
TRAF7
TRIM25
TRIM27
TRIM62
TRIM8
UBA1
UBA6
UBA7
UBE3A
44 interacting genes:
BYSL
CDC37
CRY2
DYRK4
EHHADH
ELOA
EPN2
EPN3
FAM50B
FKBP1A
GMCL1
HMG20B
HTT
IGBP1
KIF9
MEOX1
MID1IP1
MID2
N4BP1
OTUB2
PAX6
PKN1
PPP2CA
PPP2CB
PTCD2
PTPA
SPAG5
STK36
TCEANC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2K
UBE2L3
UBE2L6
UBE2N
UBE2V1
UBE2W
UBTD1
ZNF618
Entrez ID
9246
4281
HPRD ID
04867
02047
Ensembl ID
ENSG00000156587
ENSG00000101871
Uniprot IDs
O14933
A0A024RBV4
A0A087X0X0
A0A087X255
O15344
PDB IDs
1WZV
1WZW
2KJH
2DQ5
2FFW
2JUN
5IM8
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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