MID1 and OTUB2

Data Source:
BioGRID (two hybrid)

		MID1	OTUB2
Description		midline 1	OTU deubiquitinase, ubiquitin aldehyde binding 2
Image
GO Annotations	Cellular Component	Spindle Cytosol Microtubule Microtubule Associated Complex Cytoplasmic Microtubule	Nucleus
	Molecular Function	Protein Binding Microtubule Binding Zinc Ion Binding Transferase Activity Enzyme Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Homodimerization Activity Phosphoprotein Binding	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding NEDD8-specific Protease Activity Ubiquitin Binding
	Biological Process	Microtubule Cytoskeleton Organization Pattern Specification Process Positive Regulation Of Stress-activated MAPK Cascade Protein Localization To Microtubule Interferon-gamma-mediated Signaling Pathway	Protein Deubiquitination Protein Phosphopantetheinylation Protein K11-linked Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Negative Regulation Of Histone H2A K63-linked Ubiquitination Negative Regulation Of Double-strand Break Repair
Pathways		Interferon gamma signaling	Ovarian tumor domain proteases
Drugs
Diseases		Opitz-GBBB syndrome
GWAS
Interacting Genes		44 interacting genes: BYSL CDC37 CRY2 DYRK4 EHHADH ELOA EPN2 EPN3 FAM50B FKBP1A GMCL1 HMG20B HTT IGBP1 KIF9 MEOX1 MID1IP1 MID2 N4BP1 OTUB2 PAX6 PKN1 PPP2CA PPP2CB PTCD2 PTPA SPAG5 STK36 TCEANC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2L6 UBE2N UBE2V1 UBE2W UBTD1 ZNF618	42 interacting genes: APP ARRDC3 CDIP1 CPSF6 DAZAP2 FAM168A GLI2 KRT31 KRT40 LZTS2 MAGEA11 MID1 MID2 MKRN1 PHLDA2 PJA1 PLEKHB2 PMEPA1 RBCK1 REL RFFL RNF126 SIAH1 SPART TP53BP2 TRAF6 TRIM2 TRIM25 TRIM26 TRIM27 TRIM39 TRIM5 TRIM54 TRIM55 TRIM63 TRIM8 TRIP6 U2AF2 UBC UBE2N USP21 USP28
Entrez ID		4281	78990
HPRD ID		02047	07620
Ensembl ID		ENSG00000101871	ENSG00000089723
Uniprot IDs		A0A024RBV4 A0A087X0X0 A0A087X255 O15344	Q96DC9
PDB IDs		2DQ5 2FFW 2JUN 5IM8	1TFF 4FJV 5QIO 5QIP 5QIQ 5QIR 5QIS 5QIT 5QIU 5QIV 5QIW 5QIX 5QIY 5QIZ
Enriched GO Terms of Interacting Partners?
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