IVD and GPSM3

Data Source:
BioGRID (two hybrid)

		IVD	GPSM3
Description		isovaleryl-CoA dehydrogenase	G protein signaling modulator 3
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Matrix Mitochondrial Membrane	Cellular_component Cytoplasm Plasma Membrane
	Molecular Function	Butyryl-CoA Dehydrogenase Activity Protein Binding Isovaleryl-CoA Dehydrogenase Activity Identical Protein Binding Flavin Adenine Dinucleotide Binding	Molecular_function Protein Binding GTPase Regulator Activity
	Biological Process	Leucine Catabolic Process Branched-chain Amino Acid Catabolic Process Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase	Positive Regulation Of Leukocyte Chemotaxis Biological_process Positive Regulation Of Inflammatory Response Regulation Of Catalytic Activity Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Pathways		Branched-chain amino acid catabolism	G alpha (i) signalling events
Drugs		Flavin adenine dinucleotide Coenzyme A persulfide
Diseases		Isovaleric acidemia (IVA)
GWAS		Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) FEV1 ( 30804560) Idiopathic pulmonary fibrosis ( 31710517) Intelligence (MTAG) ( 29326435) Lung function (FVC) ( 30804560) Malaria ( 31844061) Metabolic traits ( 21886157)	Asthma ( 31619474) Atopic dermatitis ( 23042114 25574825) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Blood protein levels ( 28240269) Body mass index ( 31453325) Body mass index variance ( 31453325) Estimated glomerular filtration rate ( 31152163) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Inflammatory bowel disease ( 28067908) Obesity-related traits ( 23251661) Prostate cancer ( 23535732) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Ulcerative colitis ( 28067908)
Interacting Genes		4 interacting genes: ACTN3 GPSM3 MGAT5B PNMA1	45 interacting genes: ACMSD ANKRD33 ASB15 BATF2 BMF C10orf82 C11orf45 C9orf57 CHRDL2 COA7 CTAG1A CTAG1B FAM86C1P FGFR3 GATAD2B GNAI1 GNAI2 GNAI3 HELT HIGD2B HRAS HSF2BP IQCE IVD KRTAP11-1 KRTAP13-3 KRTAP19-4 MAPK7 MBD3L1 MEOX2 NR0B2 P4HA3 PRR5 RIPK4 RSPO4 SPAG8 SPRY3 STXBP5L TADA2A TEX11 UFSP1 USHBP1 YWHAZ ZNF20 ZNF581
Entrez ID		3712	63940
HPRD ID		09516	13605
Ensembl ID		ENSG00000128928	ENSG00000213654
Uniprot IDs		A0A0A0MT83 A0A0S2Z4K7 P26440	A0A024RCP6 Q9Y4H4
PDB IDs		1IVH
Enriched GO Terms of Interacting Partners?
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