CD3G and KTN1

Data Source:
BioGRID (two hybrid)

		CD3G	KTN1
Description		CD3g molecule	kinectin 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Clathrin-coated Vesicle Membrane T Cell Receptor Complex Alpha-beta T Cell Receptor Complex	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Signaling Receptor Complex Adaptor Activity T Cell Receptor Binding Identical Protein Binding Protein Heterodimerization Activity	RNA Binding Protein Binding Kinesin Binding Cadherin Binding
	Biological Process	Adaptive Immune Response Establishment Or Maintenance Of Cell Polarity Cell Surface Receptor Signaling Pathway Protein Transport Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis T Cell Activation Positive Thymic T Cell Selection Regulation Of Immune Response T Cell Receptor Signaling Pathway Membrane Organization Protein-containing Complex Assembly Regulation Of Lymphocyte Apoptotic Process	Microtubule-based Movement Protein Transport Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Downstream TCR signaling Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules FCGR activation FCGR activation Regulation of actin dynamics for phagocytic cup formation Role of phospholipids in phagocytosis PD-1 signaling Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis FCGR3A-mediated IL10 synthesis FCGR3A-mediated phagocytosis	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) RHO GTPases activate KTN1 Post-translational protein phosphorylation
Drugs		Muromonab
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Early spontaneous preterm birth ( 31194736) Lean body mass ( 28552196) Neurofibrillary tangles ( 31497858) Plasma anti-thyroglobulin levels ( 29678681) Subcortical brain region volumes ( 25607358)
Interacting Genes		14 interacting genes: CD3D CD3E EMP1 KTN1 LAT MAL PMP22 TMEM19 TMEM203 TMEM262 TMEM54 TRA TRB TRD	29 interacting genes: ABI1 BNIP3 CD3G CD68 CDC42 CLEC4C CLEC7A EEF1D FFAR2 IKBKE KIF5B KIR2DL3 LHFPL5 M6PR MEOX2 MFSD14B PDCD1LG2 PLEKHA5 RAC1 RHOA RHOG SGTA SIRPA STOM SUSD3 SYNE4 SYNPR TMEM179B UBE2I
Entrez ID		917	3895
HPRD ID		07037	02661
Ensembl ID		ENSG00000160654	ENSG00000126777
Uniprot IDs		B0YIY5 P09693	A0A024R663 Q86UP2
PDB IDs		1SY6 6JXR
Enriched GO Terms of Interacting Partners?
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