CD3G and TMEM54

Data Source:
BioGRID (two hybrid)

		CD3G	TMEM54
Description		CD3g molecule	transmembrane protein 54
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Clathrin-coated Vesicle Membrane T Cell Receptor Complex Alpha-beta T Cell Receptor Complex	Cellular_component Integral Component Of Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Signaling Receptor Complex Adaptor Activity T Cell Receptor Binding Identical Protein Binding Protein Heterodimerization Activity	Molecular_function Protein Binding
	Biological Process	Adaptive Immune Response Establishment Or Maintenance Of Cell Polarity Cell Surface Receptor Signaling Pathway Protein Transport Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis T Cell Activation Positive Thymic T Cell Selection Regulation Of Immune Response T Cell Receptor Signaling Pathway Membrane Organization Protein-containing Complex Assembly Regulation Of Lymphocyte Apoptotic Process	Biological_process
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Downstream TCR signaling Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules FCGR activation FCGR activation Regulation of actin dynamics for phagocytic cup formation Role of phospholipids in phagocytosis PD-1 signaling Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis FCGR3A-mediated IL10 synthesis FCGR3A-mediated phagocytosis
Drugs		Muromonab
Diseases
GWAS			Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269)
Interacting Genes		14 interacting genes: CD3D CD3E EMP1 KTN1 LAT MAL PMP22 TMEM19 TMEM203 TMEM262 TMEM54 TRA TRB TRD	24 interacting genes: ARL13B CD3G CLSTN3 CREB3 FKBP7 GPR152 GPR37L1 KCNJ8 KCNK5 KLRC1 LMNA MS4A14 NRG1 PEX19 PSCA PVR RBBP8 SERINC2 SLC12A7 SLC39A2 TIMMDC1 TMEM52B TSPO2 UPK1B
Entrez ID		917	113452
HPRD ID		07037	12524
Ensembl ID		ENSG00000160654	ENSG00000121900
Uniprot IDs		B0YIY5 P09693	Q969K7
PDB IDs		1SY6 6JXR
Enriched GO Terms of Interacting Partners?
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