ATPAF2 and CFAP206

Data Source:
BioGRID (two hybrid)

		ATPAF2	CFAP206
Description		ATP synthase mitochondrial F1 complex assembly factor 2	cilia and flagella associated protein 206
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Nuclear Speck	Radial Spoke Axoneme Motile Cilium Ciliary Basal Body A Axonemal Microtubule
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Proton-transporting ATP Synthase Complex Assembly	Cilium Movement Regulation Of Cilium Beat Frequency Sperm Axoneme Assembly Axoneme Assembly Regulation Of Flagellated Sperm Motility
Pathways
Drugs
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Schizophrenia ( 28991256 25056061 29483656)
Interacting Genes		73 interacting genes: AKAP8L APP ATP5F1A ATP5F1B BEGAIN C11orf1 CDC14A CDK2AP1 CEP57 CFAP206 CRTC2 CTIF CYSRT1 DDIT3 DLGAP4 EBF1 EBF3 EIF4G1 EWSR1 FAM166B FCHSD2 FNTB GOLGA6L9 IKZF3 INCA1 KRT34 KRT40 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-2 KRTAP6-3 LGALS9B LNX1 LRRFIP2 LURAP1L LZTS2 MAGEA6 MEDAG MIF4GD NME4 PAK5 PKP4 POLR2J3 POLR3F POLR3H PPP1R16B PPP1R32 PRDM14 PRDM6 RAD54B RBM48 RCN1 REL RPH3AL RPIA SORBS2 SPATC1L SPG21 TCHP TFIP11 TP53BP2 TRIM23 TRIM27 UBAP2 VWC2 WASHC1 ZFP90 ZNF19 ZNF23 ZNF35 ZNF426 ZNF655	64 interacting genes: ADAMTSL4 ANKRD55 APIP ATPAF2 BANP BLZF1 C1orf94 C9orf153 CCDC33 CDX2 CEP57L1 CFP CPSF7 CRX CYSRT1 DISC1 EIF4ENIF1 GFAP GLYR1 GPRASP2 GSE1 HOMEZ IHO1 IKZF3 KIAA1328 KLHL3 KRT31 KRT34 KRT40 KRT75 KRT76 KRTAP13-1 KRTAP26-1 LZTS2 MAGED1 MDFI MEOX2 MIF4GD NME4 PIH1D2 PRDM16 PSMA1 PSMC5 REL RNF138 ROCK1 SAMD3 SAXO1 SORBS3 SOX30 TADA2B TASOR2 TCF12 TEKT1 TFIP11 TLE5 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 VPS52 ZBTB32 ZNF511
Entrez ID		91647	154313
HPRD ID		10599	12863
Ensembl ID		ENSG00000171953	ENSG00000272514
Uniprot IDs		Q8N5M1	Q8IYR0 Q8N771
PDB IDs
Enriched GO Terms of Interacting Partners?
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