ATPAF2 and POLR3H

Data Source:
BioGRID (two hybrid)

		ATPAF2	POLR3H
Description		ATP synthase mitochondrial F1 complex assembly factor 2	RNA polymerase III subunit H
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Nuclear Speck	Nucleoplasm RNA Polymerase III Complex Centrosome Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding
	Biological Process	Proton-transporting ATP Synthase Complex Assembly	Nucleobase-containing Compound Metabolic Process Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter Positive Regulation Of Type I Interferon Production Innate Immune Response Defense Response To Virus
Pathways			Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Schizophrenia ( 28991256 25056061 29483656)	Alcohol consumption (drinks per week) ( 30679032) Bitter alcoholic beverage consumption ( 31046077) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278) Schizophrenia ( 28991256)
Interacting Genes		73 interacting genes: AKAP8L APP ATP5F1A ATP5F1B BEGAIN C11orf1 CDC14A CDK2AP1 CEP57 CFAP206 CRTC2 CTIF CYSRT1 DDIT3 DLGAP4 EBF1 EBF3 EIF4G1 EWSR1 FAM166B FCHSD2 FNTB GOLGA6L9 IKZF3 INCA1 KRT34 KRT40 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-2 KRTAP6-3 LGALS9B LNX1 LRRFIP2 LURAP1L LZTS2 MAGEA6 MEDAG MIF4GD NME4 PAK5 PKP4 POLR2J3 POLR3F POLR3H PPP1R16B PPP1R32 PRDM14 PRDM6 RAD54B RBM48 RCN1 REL RPH3AL RPIA SORBS2 SPATC1L SPG21 TCHP TFIP11 TP53BP2 TRIM23 TRIM27 UBAP2 VWC2 WASHC1 ZFP90 ZNF19 ZNF23 ZNF35 ZNF426 ZNF655	2 interacting genes: ATPAF2 CRCP
Entrez ID		91647	171568
HPRD ID		10599	15157
Ensembl ID		ENSG00000171953	ENSG00000100413
Uniprot IDs		Q8N5M1	A0A024R1P3 Q9Y535
PDB IDs
Enriched GO Terms of Interacting Partners?
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