CFAP206 and CDX2

Data Source:
BioGRID (two hybrid)

		CFAP206	CDX2
Description		cilia and flagella associated protein 206	caudal type homeobox 2
Image		No pdb structure
GO Annotations	Cellular Component	Radial Spoke Axoneme Motile Cilium Ciliary Basal Body A Axonemal Microtubule	Chromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Transcription Repressor Complex
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Methyl-CpG Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cilium Movement Regulation Of Cilium Beat Frequency Sperm Axoneme Assembly Axoneme Assembly Regulation Of Flagellated Sperm Motility	Negative Regulation Of Transcription By RNA Polymerase II Blood Vessel Development Trophectodermal Cell Differentiation Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Endosome To Lysosome Transport Embryo Development Animal Organ Morphogenesis Anterior/posterior Axis Specification Regulation Of Somitogenesis Cell Differentiation Somatic Stem Cell Population Maintenance Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription, DNA-templated Intestinal Epithelial Cell Differentiation Labyrinthine Layer Development
Pathways			Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
Drugs
Diseases
GWAS			Body mass index ( 26426971) Monocyte count ( 27863252) Pancreatic cancer ( 25086665)
Interacting Genes		64 interacting genes: ADAMTSL4 ANKRD55 APIP ATPAF2 BANP BLZF1 C1orf94 C9orf153 CCDC33 CDX2 CEP57L1 CFP CPSF7 CRX CYSRT1 DISC1 EIF4ENIF1 GFAP GLYR1 GPRASP2 GSE1 HOMEZ IHO1 IKZF3 KIAA1328 KLHL3 KRT31 KRT34 KRT40 KRT75 KRT76 KRTAP13-1 KRTAP26-1 LZTS2 MAGED1 MDFI MEOX2 MIF4GD NME4 PIH1D2 PRDM16 PSMA1 PSMC5 REL RNF138 ROCK1 SAMD3 SAXO1 SORBS3 SOX30 TADA2B TASOR2 TCF12 TEKT1 TFIP11 TLE5 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 VPS52 ZBTB32 ZNF511	16 interacting genes: ACAT2 CDK2 CFAP206 CREBBP DNMT3L EP300 GSK3B HNF1A KRTAP4-12 MAPK1 MAPK14 PAX6 SMARCA4 SMARCB1 SMARCD1 UBB
Entrez ID		154313	1045
HPRD ID		12863	02622
Ensembl ID		ENSG00000272514	ENSG00000165556
Uniprot IDs		Q8IYR0 Q8N771	Q99626
PDB IDs			5LTY 6ES2 6ES3
Enriched GO Terms of Interacting Partners?
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